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Home › Conditions › Stress, Psychological

Stress, Psychological

Subtypes of Stress, Psychological

Burnout 3 Caregiver Burden 1

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Stress, Psychological

30 trials tracked for Stress, Psychological: 2 in phase 3 or 4 and 1 with published results. The most-cited published study has 28 citations.

30Trials tracked
2Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 2 Phase 2 2 Other / NA 26
  1. Phase 4 Does Propranolol Attenuate Inflammatory Responses to a Psychological Stressor? Completed · 28 cited
  2. Phase 4 Brain and Stress Study Completed
  3. Phase 2 Inhaled Oxytocin and HPA Axis Reactivity Completed
  4. Phase 2 Auriculotherapy as a Coping Strategy in Professional Nursing Completed
  5. N/A Stay Healthy In Nature Everyday: Family Nature Outings in a Low Income Population Completed
  6. N/A Compassion-Based Resiliency Training (CBRT) Intervention on Racism-based Stress Completed
Show 24 more trials
  1. N/A A Randomized Placebo Controlled Pilot Study of Probiotic Supplementation in At-risk Pregnant Women Completed
  2. N/A Brief Mindfulness Meditation Course to Reduce Stress in Healthcare Professionals Completed
  3. N/A Stress and Sleep Study Completed
  4. N/A Mobile Web-based Behavioral Intervention for Improving Caregiver Well-being Completed
  5. N/A Stress and Hypertension in Dementia Caregivers Completed
  6. N/A Mindfulness-based Stress Reduction for Urban Youth Completed
  7. N/A Digital Behavioral Interventions in Inflammatory Bowel Disease Completed
  8. N/A Intervention to Reduce Stress in 0-5 Year Olds With Burns Completed
  9. N/A Family-centered Mental Health Promotion Intervention Completed
  10. N/A Wellness Coaching for Caregivers of Thoracic Transplant Candidates Completed
  11. N/A Adolescent Responses to Varying Environments in Virtual Reality Simulations Completed
  12. N/A Yoga and Aerobic Exercise Effects on Cognition Completed
  13. N/A Emotion-Diet Interactions in Pregnancy Completed
  14. N/A Caring for Providers to Improve Patient Experience Study Phase 2 in Migori County Completed
  15. N/A Development of An Exergame for Caregivers of Individuals With Alzheimer's Disease or Related Dementias Completed
  16. N/A Ecological Momentary Assessment and Text Message Intervention for Stress Management Completed
  17. N/A Rural Dementia Caregiver Project Completed
  18. N/A Mindfulness-Based Resilience Training for Aggression, Health, and Stress Among Law Enforcement Officers Completed
  19. N/A Does an Occupational Therapy Program Enhance Mental Health Outcomes for Veterans Who Scuba Dive Completed
  20. N/A Testing a Digital Intervention for Adolescents Completed
  21. N/A OUR Stress/ Emotion Management for Black/African American Women With Hypertension Completed
  22. N/A Proximal Effects of Alcohol on Same-Sex Intimate Partner Violence Completed
  23. N/A Audiovisual Aid Pilot Study Completed
  24. N/A Stress & Anxiety Dampening Effects of a Probiotic Supplement Compared to Placebo in Healthy Subjects Completed

Showing the 30 most-cited and recently-updated of 30 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Stress, Psychological: what the trials found

Clinical trials evaluated the efficacy of pharmacological interventions for stress-related conditions. Propanolol hydrochloride was investigated in a Phase 4 trial 2.

Minocycline was evaluated in a Phase 4 trial; however, no statistically significant changes were observed in response bias during probabilistic reward tasks (p=0.856), Snaith Hamilton Pleasure Scale scores (p=1.000), or Motivation and Pleasure Scale scores (p=0.225) 3.

Recent results — preliminary, needs further review

  • Contemplative-Based Resilience Training (CBRT) was evaluated, but no statistically significant changes were found in Allostatic Load Composite Scores (p=0.135), Cortisol Awakening Response (p=0.395), or CTRA Gene Expression scores (p=0.93) 1.
  • mPEP 6, Sun salutations 7, and psychosocial stress 8 were also investigated in recent trials.

For the clinician treating this condition

  • Propanolol hydrochloride is an established pharmacological intervention for stress-related conditions 2.
  • Minocycline did not demonstrate significant improvements in pleasure, motivation, or reward-based response biases in the studied population 3.

AI synthesis of 6 cited trials, updated Aug 20, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Psychological capital, research competence, and social support correlate negatively with ICU nurse burnout
Primary Care & Family Medicine Meta-analysis
Psychological capital, research competence, and social support correlate negatively with ICU nurse burnout Support and skills help reduce burnout in ICU nurses
This meta-analysis of 31 studies involving 8,219 ICU nurses in China found that psychological capital (r = -0.43), research competence (r = …
New data shows that social support and personal confidence can lower burnout levels for nurses working in intensive care units.
Frontiers Aug 5, 2026
Meta-analysis suggests VR interventions reduce stress and anxiety in healthcare workers
Primary Care & Family Medicine Meta-analysis
Meta-analysis suggests VR interventions reduce stress and anxiety in healthcare workers Can virtual reality help healthcare workers feel less stressed and anxious right now?
This PRISMA-guided systematic review and meta-analysis pooled 10 studies (493 healthcare workers) examining virtual reality interventions fo…
Virtual reality lowered stress and anxiety scores by 0.64 points for healthcare workers in a new review of 493 participants.
Frontiers Apr 16, 2026
Scoping review identifies operational and organizational drivers of burnout in public safety personnel
Psychiatry Sys. Review
Scoping review identifies operational and organizational drivers of burnout in public safety personnel Why do we know so little about moral injury in first responders?
A scoping review of 43 studies examined burnout and moral injury drivers in public safety personnel (EMTs, firefighters, dispatchers).
While burnout gets studied, moral injury in first responders is almost ignored, leaving a critical gap in how we help EMTs and firefighters.
Frontiers Apr 3, 2026
Scoping review identifies 19 factors influencing caregiver support for older adults in rural areas
Geriatrics & Aging Sys. Review
Scoping review identifies 19 factors influencing caregiver support for older adults in rural areas What makes caregiving in rural areas so hard? A review finds 19 key challenges
A scoping review of 25 studies examined factors influencing caregiver support within integrated care for older adults in rural areas.
Rural caregivers face 19 specific hurdles like isolation, money worries, and poor internet access that make supporting aging parents incredi…
Frontiers Apr 3, 2026