N/A Completed N=3,512 Randomized Single-blind Screening

Models of Primary Osteoporosis Screening in Male Veterans

Osteoporosis · osteopenia · Osteoporotic fractures

Source: ClinicalTrials.gov NCT04079868 ↗

Enrolled (actual)

3,512

Serious AEs

0.0%

Results posted

Oct 2025

Primary outcomePrimary: Proportion of Participants Screened for Osteoporosis — 830; 33 participants

Summary

Models of Osteoporosis Screening in Male Veterans aims to test 1 distinct care model of primary osteoporosis screening in men within the VA healthcare setting. All care models deliver VA recommended osteoporosis screening and treatment to high-risk Veterans by appropriate Durham VA clinical staff. The MOPS project will evaluate patient, provider and facility outcomes to determine the effectiveness of each intervention.

Outcome Measures

Outcome	Result	p-value
PRIMARY Proportion of Participants Screened for Osteoporosis	830; 33	—
PRIMARY Bone Mineral Density T-score at the Femoral Neck	-0.55; -0.70	—
SECONDARY Gastrointestinal Medication Prescriptions	562; 473	—
SECONDARY Osteoporosis Medication Adherence (Proportion of Days Covered)	0.92; 1.0	—
SECONDARY Proportion of Patients Initiating Osteoporosis Medication (%)	113; 4	—
SECONDARY Osteoporosis Medication Persistence (Days)	657; 730	—
SECONDARY Proportion With Fractures	31; 29	—

Eligibility Criteria

Inclusion Criteria

PACT Team inclusion criteria:

Provider with at least 0.75 FTE
Provider has completed training (i.e., PACT teams led by residents and fellows are excluded)
Care for male Veterans >65 years (i.e., Women's Health PACTs are excluded)

Patient Inclusion criteria:

No prior fracture or osteoporosis diagnosis
At least 1 VA Undersecretary Guideline risk factor (weight loss >20% in 5 years; BMI <25 kg/m2; diabetes; pernicious anemia; gastrectomy; anticonvulsants; glucocorticoids; androgen deprivation therapy; hyperthyroidism; hyperparathyroidism; rheumatoid arthritis; alcohol dependence; chronic lung disease; chronic liver disease; stroke; Parkinsonism; prostate cancer; and current smoking).

Patients (enrolled in year 4/5 sub-sample) inclusion criteria:

Men aged 65-85 years
Enrolled in eligible PACT team for at least 2 years
Meet 1 or more criteria for osteoporosis screening as the protocol at PACT enrollment.

Exclusion Criteria

None

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04079868). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.