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N/A N=3,512 Randomized Single-blind Screening

Models of Primary Osteoporosis Screening in Male Veterans

Osteoporosis · Osteopenia · Osteoporotic Fracture

Enrolled (actual)
3,512
Serious AEs
0.0%
Results posted
Oct 2025
Primary outcome: Primary: Proportion of Participants Screened for Osteoporosis — 830; 33 participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Bone Health Service Model (Behavioral)
Age
Pediatric, Adult, Older Adult
Sex
All
Sponsor
VA Office of Research and Development
Primary completion
Aug 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Proportion of Participants Screened for Osteoporosis
830; 33
PRIMARY
Bone Mineral Density T-score at the Femoral Neck
-0.55; -0.70
SECONDARY
Gastrointestinal Medication Prescriptions
562; 473
SECONDARY
Osteoporosis Medication Adherence (Proportion of Days Covered)
0.92; 1.0
SECONDARY
Proportion of Patients Initiating Osteoporosis Medication (%)
113; 4
SECONDARY
Osteoporosis Medication Persistence (Days)
657; 730
SECONDARY
Proportion With Fractures
31; 29

Summary

Models of Osteoporosis Screening in Male Veterans aims to test 1 distinct care model of primary osteoporosis screening in men within the VA healthcare setting. All care models deliver VA recommended osteoporosis screening and treatment to high-risk Veterans by appropriate Durham VA clinical staff. The MOPS project will evaluate patient, provider and facility outcomes to determine the effectiveness of each intervention.

Eligibility Criteria

Inclusion Criteria

PACT Team inclusion criteria:

  • Provider with at least 0.75 FTE
  • Provider has completed training (i.e., PACT teams led by residents and fellows are excluded)
  • Care for male Veterans >65 years (i.e., Women's Health PACTs are excluded)

Patient Inclusion criteria:

  • No prior fracture or osteoporosis diagnosis
  • At least 1 VA Undersecretary Guideline risk factor (weight loss >20% in 5 years; BMI <25 kg/m2; diabetes; pernicious anemia; gastrectomy; anticonvulsants; glucocorticoids; androgen deprivation therapy; hyperthyroidism; hyperparathyroidism; rheumatoid arthritis; alcohol dependence; chronic lung disease; chronic liver disease; stroke; Parkinsonism; prostate cancer; and current smoking).

Patients (enrolled in year 4/5 sub-sample) inclusion criteria:

  • Men aged 65-85 years
  • Enrolled in eligible PACT team for at least 2 years
  • Meet 1 or more criteria for osteoporosis screening as the protocol at PACT enrollment.

Exclusion Criteria

None

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04079868). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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