Questions about Osteoporosis
Can MRI scans and machine learning predict osteoporosis and abnormal bone density?
Yes, MRI scans combined with machine learning can predict osteoporosis and abnormal bone density with high accuracy, often matching or exceeding CT-based methods.
Full answer →Can VBQ scores and Hounsfield Units predict fractures after vertebral augmentation?
Yes, both VBQ scores and Hounsfield Units can predict fractures after vertebral augmentation, with VBQ showing slightly better sensitivity.
Full answer →Does romosozumab improve bone strength in postmenopausal women with osteoporosis?
Yes, romosozumab improves bone strength in postmenopausal women with osteoporosis, as shown by increases in shear bone strength, volumetric BMD, and trabecular bone score in clinical trials.
Full answer →All Osteoporosis Articles
- Standardized protocols for OVX rat models are necessary to reduce high heterogeneity in bone density data
- Gut microbiota and its products regulate bone metabolism through the gut-immune-bone axis
- Efficacy of Chinese Polyherbal Preparations Combined with Biomedicine for Diabetic Osteoporosis
- Immunosenescence drives pro-inflammatory immune shifts and impaired bone remodeling in osteoporosis
- RAAS inhibitors modulate inflammatory responses and oxidative stress across multiple chronic conditions
- Microbiota-directed interventions show inconsistent clinical efficacy for reducing fracture risk in osteoporosis
- Chinese osteoporosis management guidelines show consensus on diagnosis but vary in specific treatment recommendations
- Chinese clinical practice guidelines for osteoporosis demonstrate moderate methodological and recommendation quality scores
- German translation and adaptation of the APTA Geriatrics guideline provides a basis for evidence-based physiotherapy
- Gut microbiota and metabolic products regulate bone homeostasis and immune checkpoints in osteoporosis
- Exercise improves balance function in patients with osteoporosis with larger effects for longer durations
- TCM combined with Western therapy improves BMD and FEV1 in patients with COPD and osteoporosis
- Osteoporosis prevalence is 22.0% and low bone mass is 41.7% in men with prostate cancer
- Pooled prevalence of osteosarcopenia in postmenopausal women is 15.6% across diverse settings
- Exercise therapy for osteoporosis faces significant translational gaps and heterogeneous osteogenic effects across modalities
- Age, smoking, and diabetes are associated with increased risk of postmenopausal osteoporosis
- Ferroptosis serves as a mechanistic link between metabolic stress and bone remodeling dysfunction in osteoporosis
- Immune cells and bone lineage cells interact via cytokines to modulate bone homeostasis in musculoskeletal disorders
- Gut Microbiota-NGF-Bone Axis Proposed as Conceptual Framework for Postmenopausal Osteoporosis
- Bangga extracts show antibacterial, anti-inflammatory, antiviral, and antitumor activity in preclinical synthesis
- Coumarins and derivatives may protect musculoskeletal health by modulating inflammatory and oxidative mediators
- Potent bisphosphonate therapy reduces incident vertebral fractures by 71% after denosumab discontinuation
- CDAI and SDAI scores improve prediction of osteoporosis in patients with rheumatoid arthritis
- Senolytics like dasatinib and quercetin show promise for improving skeletal parameters in osteoporosis models
- Nutrition-related laboratory biomarkers provide risk stratification for geriatric patients with hip fractures
- Pharmacist-led medication therapy management improves adherence and glycemic control in a patient with complex T2DM
- Indole derivatives regulate bone homeostasis via gut-bone axis in osteoporosis
- Hormonal suppression for endometriosis may cause bone mineral density loss while untreated cases show no deficits
- CircRNAs demonstrate high diagnostic accuracy for osteoporosis with an AUC of 0.91
- Curcumin raises femoral bone density in animal osteoporosis models, meta-analysis finds
- Glucocorticoid use and rheumatoid arthritis significantly increase vertebral fracture risk in postmenopausal women
- Bibliometric Mapping Analysis Reveals Evolving Research Trends in Scoliosis and Osteoporosis Management
- Gut microbiota interventions may modulate bone metabolism and influence progression of postmenopausal osteoporosis
- The osteoimmune-brain axis links systemic inflammation and bone hormones to neurodegenerative pathology
- Locking plate fixation and arthroplasty are key treatments for osteoporotic proximal humeral fractures
- Circadian misalignment associated with increased risk of osteoporosis, sarcopenia, and osteoarthritis
- Chinese botanical drugs may improve bone metabolism by modulating the gut-bone axis in osteoporosis
- CD8+ T cells and associated signaling pathways influence osteoclast formation and osteoblast differentiation in osteoporosis
- Novel osteoporosis therapies targeting osteoclast fusion and polarization show promise beyond bisphosphonates
- Physical exercise therapy may support osteosarcopenia management in elderly patients according to this narrative review
- Network meta-analysis reveals optimal aerobic exercise frequency and intensity for improving bone mineral density in osteoporosis patients
- Drug-induced osteoporosis mechanisms and gut microbiota links remain largely unresolved for most medication classes
- Gut microbiome metabolites regulate bone health via SCFAs, bile acids, and tryptophan pathways
- Narrative review on polysaccharide metabolites from kidney-tonifying TCM for osteoporosis
- Systematic review and meta-analysis of Salvia miltiorrhiza for osteoporosis in animal models
- Systematic review finds little fracture prevention benefit from calcium or vitamin D in low-risk adults
- Narrative review on gut-bone axis biomaterials for osteoporosis therapy
- Narrative review examines Chinese botanical drugs for osteoporosis without reported clinical data
- Review of senescence-associated secretory phenotype in aging osteoarthritis and disc degeneration
- Network meta-analysis compares osteoporosis drugs for bone density in men
- Romosozumab improves shear bone strength in postmenopausal women with osteoporosis in BCT substudies
- VBQ and Hounsfield Units Predict Subsequent Fractures After Vertebral Augmentation
- Systematic Review and Meta-Analysis Links α-Klotho to Frailty and Bone Health in Aging
- Nomogram Predicts Osteoporosis Risk in Rheumatoid Arthritis Patients
- Machine learning radiomics on MRI sequences predicts osteoporosis and abnormal bone density in retrospective cohort
- Narrative review examines coronary risk and vascular effects of bisphosphonates, denosumab, and romosozumab in osteoporosis
- Narrative review explores gut metabolites postbiotics obesity fatty liver and bone loss associations
- Meta-analysis of preclinical studies supports kaempferol for osteoporosis
- L1 Cortical Bone Quantitative CT Parameters Show Association With Osteoporosis in 169 Patient Cohort
- Narrative review links gut dysbiosis and immune changes to osteoporosis mechanisms in postmenopausal women and older adults
- Higher Geriatric Nutritional Risk Index linked to lower osteoporosis risk in diabetic women
- Review examines current endocrine causes of secondary osteoporosis and clinical management approaches
- Narrative review discusses Erzhi Pill for osteoporosis and menopausal syndrome with noted limitations
- Machine learning model using 32 variables predicts osteoporotic fractures in postmenopausal women
- Narrative review explores engineered exosomes for bone disorders, notes translational challenges
- Meta-analysis links long-term glucocorticoid use and SLE duration to high osteoporosis prevalence in patients
- Systematic review of osteoporosis interventions reports mixed outcomes with no specific medication data provided
- PCKP reduces early pain and leakage versus UPKP in osteoporotic vertebral fractures
- Review of quercetin in metabolic diseases shows promise but lacks clinical validation
- Systematic review links gut microbiota dysbiosis to CKD-MBD, RA, OA, and OP pathogenesis
- In male osteoporosis, anabolic therapies improved lumbar spine and hip BMD more than antiresorptives at 12 months
- Systematic review examines angiogenesis-targeting strategies for osteoporosis and fracture healing
- Resistance training improves quality of life in older adults with osteoporosis, meta-analysis finds
- Denosumab showed no effect on periprosthetic bone density five years after uncemented total hip arthroplasty
- Retrospective study finds inverse association between NHHR and osteoporotic fracture risk