N/A
N=301
Power-Up: An Effectiveness Trial of the Diabetes Prevention Program
Type 2 Diabetes · Pre-Diabetes
Bottom Line
View on ClinicalTrials.gov: NCT04104243 ↗Enrolled (actual)
301
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcome: Primary: Percent Weight Change Through 16 Sessions — -2.4; -1.3; -1.5; -1.6 percent weight change
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Men-Tailored DPP (Power-Up) (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- Male
- Sponsor
- Albert Einstein College of Medicine
- Primary completion
- Feb 2025
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percent Weight Change Through 16 Sessions |
-2.4; -1.3; -1.5; -1.6; -2.4; -1.8 | — |
| PRIMARY Percent Weight Change Through the 12 Month Trial |
-2.6; -0.7; -0.9; -0.9; -1.8; -1.8 | — |
| SECONDARY Engagement of Men in Power-Up vs Standard National Diabetes Prevention Program |
100; 97; 55; 49 | 0.1228 |
| SECONDARY Retention of Men in Power-Up vs Standard National Diabetes Prevention Program |
106; 108; 49; 38 | 0.285 |
Summary
The goal of this study is to address the risk of diabetes among men by creating a Diabetes Prevention Program (DPP) tailored to men.
Eligibility Criteria
Inclusion Criteria
- At least 18 years old
- Most recent HbA1c: 5.7%-6.4% (within last year) or Diabetes Risk Score >= 5
- Most recent BMI ≥ 25 (within last 6 months)
- Access to a device that can join sessions virtually either through a virtual conferencing application
- Have valid address and telephone contact information
- Have no plans to change their health system/primary care provider or move from their current, NYC area, address in the next year
Exclusion Criteria
- Not physically able or willing to attend virtual, group-based sessions
- Unable to provide informed consent by telephone
- Unable or unwilling to complete baseline telephone surveys or follow-up surveys in English or Spanish
Data sourced from ClinicalTrials.gov (NCT04104243). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.