N/A
N=106,629
Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care
Sepsis
Bottom Line
View on ClinicalTrials.gov: NCT04148989 ↗Enrolled (actual)
106,629
Serious AEs
0.0%
Results posted
Mar 2024
Primary outcome: Primary: Door-to-antibiotic Time — 160; 146; 139; 140 minutes — p=<0.001
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Code Sepsis protocol (full implementation) (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Intermountain Health Care, Inc.
- Primary completion
- Jan 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Door-to-antibiotic Time |
160; 146; 139; 140 | <0.001 sig |
| SECONDARY All-cause 30-day Mortality |
201; 262; 280; 332 | 0.45 |
| SECONDARY All-cause 1-year Mortality |
467; 483; 603; 628 | 0.10 |
| SECONDARY All-cause In-hospital Mortality |
113; 148; 149; 190 | 0.15 |
| SECONDARY Hospital Charges |
7.3; 15.0; 7.6; 15.2 | 0.71 |
| SECONDARY Hospital Length of Stay |
2.7; 3.0; 2.7; 2.9 | 0.19 |
Summary
Sepsis is a life-threatening complication of infection that can be difficult to recognize and treat promptly. Timely administration of antibiotics for emergency department (ED) patients with sepsis is challenging. The goal of this study is to determine the potential effectiveness and unintended consequences of reorganizing ED care for patients with suspected sepsis.
Eligibility Criteria
Inclusion criteria (overall):
- Adult (age ≥18 years)
- ED patient at Intermountain Medical Center, Utah Valley Hospital, Dixie Regional Medical Center
- Arrival to study emergency department (ED) during study period of 11/13/2018 to 2/12/2021.
Exclusion criteria (overall):
(1) Trauma patient
Data sourced from ClinicalTrials.gov (NCT04148989). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.