N/A
Completed N=106,629
Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care
Source: ClinicalTrials.gov NCT04148989 ↗Enrolled (actual)
106,629
Serious AEs
0.0%
Results posted
Mar 2024
Primary outcomePrimary: Door-to-antibiotic Time — 160; 146; 139; 140 minutes — p=<0.001
Summary
Sepsis is a life-threatening complication of infection that can be difficult to recognize and treat promptly. Timely administration of antibiotics for emergency department (ED) patients with sepsis is challenging. The goal of this study is to determine the potential effectiveness and unintended consequences of reorganizing ED care for patients with suspected sepsis.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Door-to-antibiotic Time |
160; 146; 139; 140 | <0.001 sig |
| SECONDARY All-cause 30-day Mortality |
201; 262; 280; 332 | 0.45 |
| SECONDARY All-cause 1-year Mortality |
467; 483; 603; 628 | 0.10 |
| SECONDARY All-cause In-hospital Mortality |
113; 148; 149; 190 | 0.15 |
| SECONDARY Hospital Charges |
7.3; 15.0; 7.6; 15.2 | 0.71 |
| SECONDARY Hospital Length of Stay |
2.7; 3.0; 2.7; 2.9 | 0.19 |
Eligibility Criteria
Inclusion criteria (overall):
- Adult (age ≥18 years)
- ED patient at Intermountain Medical Center, Utah Valley Hospital, Dixie Regional Medical Center
- Arrival to study emergency department (ED) during study period of 11/13/2018 to 2/12/2021.
Exclusion criteria (overall):
(1) Trauma patient
Data sourced from ClinicalTrials.gov (NCT04148989). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.