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N/A N=342 Single-blind Basic Science

Study 1 Replication and Extension of Prior Work

Autism Spectrum Disorder

Enrolled (actual)
342
Serious AEs
0.0%
Results posted
Mar 2025
Primary outcome: Primary: Number of Children Who Select the Target Object as Measured by Gaze Preference. — 47; 44; 71; 56 Participants — p=<0.01

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Overheard Speech (Behavioral); Addressed Speech (Behavioral)
Age
Pediatric · 0+ yrs
Sex
All
Sponsor
New York University
Primary completion
Dec 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Children Who Select the Target Object as Measured by Gaze Preference.
44; 31; 54; 58 <0.01 sig
PRIMARY
Number of Children Who Select the Target Object as Measured by Gaze Preference.
44; 31; 54; 58 <0.01 sig

Summary

The goal of this research is to explore abilities to learn word meanings from overheard conversations in children with ASD (and, as a control, typically developing children). Specific Aim 1 (Experiment 1): Subaim 1a: Identify child characteristics associated with learning from overhearing. In a prior study, the investigators found that 13 children with ASD were able to learn the meanings of novel words that they heard used in a conversation involving two adults. In the current study, the investigators aim to study a larger sample to identify what child characteristics are associated with good learning in an overhearing situation as compared to a situation in which the child is directly taught the new word. Subaim 1b: Assess retention and generalization of words learned from overhearing. The investigators will re-test children on their knowledge of the word meanings after a 10-minute delay to see if they both retain the word meanings and can generalize the new words to new situations.

Eligibility Criteria

Inclusion Criteria

  • children with or without a diagnosis of ASD between 18 to 71 months of age

Exclusion Criteria

  • native language is not English
  • born premature (< 36 weeks)
  • has uncorrected hearing or vision impairments
  • has developmental disorders or medical conditions other than ASD that affect language or cognition (excepting psychiatric conditions often comorbid with ASD such as ADHD)
  • has a history of photosensitive epileptic seizures
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04166591). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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