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Phase 4 Completed N=75 Randomized Triple-blind Treatment

Sublingual Sufentanil vs Intravenous Fentanyl for Acute Pain in the Ambulatory Surgery Center

Postoperative Pain · Pain, Acute · Anesthesia
Source: ClinicalTrials.gov NCT04177862 ↗
Enrolled (actual)
75
Serious AEs
0.0%
Results posted
Feb 2021
Primary outcomePrimary: Recovery Room Time — 73.0; 65.0 minutes
◆ Published Evidence
No publication linked

No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.

Summary

The purpose of this study is to determine if a single dose of sublingual sufentanil is as or more efficacious than a single dose of IV fentanyl in a post anesthesia care setting.

Outcome Measures

OutcomeResultp-value
PRIMARY
Recovery Room Time
73.0; 65.0
SECONDARY
Rescue Milligram Morphine Equivalents (Opioid Use After Intervention Until Discharge)
15.0; 22.5
SECONDARY
Adverse Events
0; 0
SECONDARY
Postoperative Nausea and Vomiting (PONV)
4; 7
SECONDARY
Supplemental Oxygen
4; 4
SECONDARY
Overall Benefit of Analgesic Score (OBAS)
3.0; 3.0

Eligibility Criteria

Inclusion Criteria

  • undergoing outpatient ambulatory surgery
  • recipient of general anesthesia
  • pain score of 4 or greater in the PACU

Exclusion Criteria

  • non-english speaking patients
  • cancer surgeries
  • patients who have allergy or intolerance to the study drugs or derivatives
  • patients on chronic opioids (defined as daily opioids for 3 months or longer)
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04177862). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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