N/A
N=61
Patients With Chronic Knee Pain Treated With Conventional Radiofrequency of the Genicular Nerves
Chronic Knee Pain
Bottom Line
View on ClinicalTrials.gov: NCT04234984 ↗Enrolled (actual)
61
Serious AEs
1.7%
Results posted
Jun 2022
Primary outcome: Primary: The Number of Patients Reaching Treatment Succes at 6 Weeks Defined as Global Perceived Effect (GPE) of ≥ 50% Compared to Baseline. — 4; 15 Participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Ziekenhuis Oost-Limburg
- Primary completion
- Nov 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Number of Patients Reaching Treatment Succes at 6 Weeks Defined as Global Perceived Effect (GPE) of ≥ 50% Compared to Baseline. |
4; 15 | — |
| SECONDARY The Number of Participants With NRS Reduction ≥50% Compared to Baseline |
4; 9 | — |
| SECONDARY The Patient's NRS |
5.6; 7.3; 2.8; 3.4; 7.1; 7.5 | — |
| SECONDARY The Number of Patients With Subjective Increase in Physical Functioning at the Second Time Point |
1; 6 | — |
| SECONDARY The Number of Pariticipants Using Strong Opioids |
3; 8; 1; 3; 2; 5 | — |
| SECONDARY Strong Opioid Use at the Second Time Point |
1; 5 | — |
| SECONDARY The Number of Participants Reaching Treatment Success After Retrieval of the Informed Consent Defined as GPE of ≥ 50% Compared to Baseline. |
2; 4 | — |
| SECONDARY Number of Participants With Post-treatment Complications |
0; 1; 0; 0 | — |
| SECONDARY Number of Participants With Post-treatment Complications |
0; 1; 0; 0 | — |
Summary
Management of chronic knee pain remains a challenge to the treating physician. A radiofrequency treatment of the genicular nerves is a not yet established but promising technique. This procedure is minimal invasive and has few adverse events. For these reasons it can be advantageous and fulfilling the unmet needs of these chronic knee pain patients warranting further research of its efficacy.
To investigate this efficacy, all patients treated with radiofrequency ablation in the multidisciplinary chronic pain center between 1 September 2017 and 31 December 2019 with exclusion of patients with chronic widespread pain, will be retrospectively analyzed in a single-center cohort.
Eligibility Criteria
Inclusion Criteria
- All patients with chronic knee pain who qualify for a conventional RF treatment of the genicular nerves
Exclusion Criteria
- A negative diagnostic block with lidocaine 2% 1 ml of the three genicular nerves defined as less than 50% pain reduction
- Chronic widespread pain
Data sourced from ClinicalTrials.gov (NCT04234984). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.