N/A
Completed N=36
Incentives to Decrease Opioid Use - Pilot
Substance-Related Disorders · Opioid-Related Disorders · Behavior Therapy
Source: ClinicalTrials.gov NCT04235582 ↗
Enrolled (actual)
36
Serious AEs
0.0%
Results posted
Aug 2021
Primary outcomePrimary: Continuous Abstinence From Opioid Use — 6; 5; 5 Participants
Summary
The purpose of this study is to address two key questions in the literature on incentives for substance use. The first question is whether it is more effective to directly incentivize the outcome of interest - drug abstinence - or to incentivize behaviors that are inputs into the production of abstinence. This study will compare two versions of the incentive program: one that incentivizes inputs to achieving abstinence and one that incentivizes the outcome of abstinence. The second question is how to optimize the size of incentives over time to maximize incentive effectiveness. This will be done by randomly varying the size and timing of incentives offered to participants in both the Inputs and Outcomes groups. The incentive amounts will then be varied across participants and time to fit a structural model of abstinence behaviors over time. The model will be used to describe the optimal shape of incentives over time.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Continuous Abstinence From Opioid Use |
6; 5; 3 | — |
| PRIMARY Continuous Abstinence From Opioid Use |
6; 5; 3 | — |
| PRIMARY Opioid-negative Saliva Tests at Week 12 |
6; 5; 3 | — |
Eligibility Criteria
Inclusion
- Age at least 18 years old;
- Meet DSM-5 opioid use disorder criteria as evidenced by an opioid disorder CPT code F11 (opioid related disorders);
- Have access to a smartphone (iOS or Android) with data plan and willing to download DynamiCare app;
- Are in day (PHP) or partial day (IOP) AODA treatment in Aurora Health's Behavioral Health Program;
- Are currently prescribed or will be prescribed within 1-4 days oral buprenorphine for their OUD;
- Are likely to be helped by contingency management because at least ONE of the following conditions is true:
- Were first enrolled in day or partial day opioid treatment no longer than 1 week prior to providing informed consent.
- Currently using non-medical opioids.
- Regularly missing scheduled AODA appointments.
- Understands English.
Exclusion Criteria
- Have evidence of active (non-substance related) psychosis that might impair participation as determined by the PI.
- Has significant cognitive impairment that might confound participation as determined by the PI or are so significantly cognitively impaired that they have a legal guardian.
Note that pregnant women are not excluded from participating in the study
Data sourced from ClinicalTrials.gov (NCT04235582). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.