N/A
N=170
Comparing Two Types of Endometrial Activation Prior to Embryo Transfer
Infertility · Endometrial Disorder
Bottom Line
View on ClinicalTrials.gov: NCT04363879 ↗Enrolled (actual)
170
Serious AEs
0.0%
Results posted
May 2020
Primary outcome: Primary: Number of Participants With Live Births Per Transfers Performed — 37; 43 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Endometrial scratch with Pipelle curette (Procedure); Endometrial scratch with Shepard catheter (Procedure)
- Age
- Adult · 18+ yrs
- Sex
- Female
- Sponsor
- Wake Forest University Health Sciences
- Primary completion
- Jul 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Live Births Per Transfers Performed |
37; 43 | — |
| SECONDARY Pain Quantifcation After Endometrial Scratch |
3.9; 3.0 | — |
| SECONDARY Number (Count) of Positive Pregnancy Tests Per Number of Subjects Undergoing Embryo Transfer |
56; 62 | — |
| SECONDARY Number (Count) of Pregnancies Per Number of Patients Undergoing Embryo Transfer |
44; 55 | — |
Summary
To determine if two types of endometrial activation (Pipelle curette or Shepard catheter) prior to embryo transfer result in similar live birth rates. Also to determine if patients experience similar pain from both types of endometrial activation.
Eligibility Criteria
Inclusion Criteria
- All patients undergoing embryo transfer who are in the cycle prior to their embryo transfer
Exclusion Criteria
- Patients not undergoing embryo transfer
- Known pregnancy
- Active pelvic infection
- Known endometrial hyperplasia or cancer
- Inability to tolerate endometrial catheter placement
- Severe cervical stenosis
- Patients who will receive operative hysteroscopy in the cycle prior to embryo transfer
Data sourced from ClinicalTrials.gov (NCT04363879). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.