N/A
N=17
Randomized Study of Daytime vs. Delayed Eating: Effect on Weight and Metabolism
Obesity
Bottom Line
View on ClinicalTrials.gov: NCT04414644 ↗Enrolled (actual)
17
Serious AEs
0.0%
Results posted
Mar 2025
Primary outcome: Primary: Body Mass Changes Between the Daytime vs. Delayed Eating Conditions — -1.1; 0.2 kg
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Eating Condition (Behavioral)
- Age
- Adult · 21+ yrs
- Sex
- All
- Sponsor
- University of Pennsylvania
- Primary completion
- Jun 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Body Mass Changes Between the Daytime vs. Delayed Eating Conditions |
-1.1; 0.2 | — |
| SECONDARY Respiratory Quotient Changes in the Daytime vs Delayed Eating Conditions |
-.012; -.021 | — |
| SECONDARY Energy Expenditure Changes Between the Daytime and Delayed Eating Conditions |
-93.66; 24.35 | — |
Summary
The purpose of this study is to determine if, controlling for eating and sleep timing, caloric intake, and exercise, daytime vs. delayed eating affects body mass, adiposity, and energy metabolism in healthy adults.
Eligibility Criteria
Inclusion Criteria
- Adults of all races and ethnicities
- Age 21-45; BMI 20-27 kg/m2
- stable weight (+/- 10 lbs) over the previous 6 months
- Women must be pre-menopausal with regular menstrual cycles.
Exclusion Criteria
- Regular exercise more than 3 d/wk, for 30 min measured by exercise logs and actigraphy
- normal activity levels are required throughout the study (+/-30 min/wk of baseline level).
- Unstable, serious medical conditions
- use of medicine linked to weight gain/loss
- cancer, diabetes, or autoimmune disease
- use of illicit drugs, melatonin, diuretics or hypnotics
- current weight loss program; presence of a sleep disorder (determined by surveys and actigraphy)
- night shift work; extreme chronotypes (extreme larks or night owls)
- habitual waking outside of 0600 h-0930h
- habitual bedtime outside of 2200h to 2400h
- sleep duration outside of 6.5 to 8.5 h/night.
- Psychiatric exclusions will be depression (Patient Health Questionnaire-9 score 9), lifetime bipolar disorder, psychosis, or lifetime eating disorder; or any other severe psychiatric disorder judged to interfere with study adherence as assessed by the Structured Clinical Interview for the DSM-IV.
Data sourced from ClinicalTrials.gov (NCT04414644). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.