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N/A N=99 Randomized Single-blind Prevention

Postpartum Wellness

Postpartum Depression

Enrolled (actual)
99
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcome: Primary: Depression Symptoms — 10.1; 11 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Exercise intervention (Behavioral)
Age
Adult · 18+ yrs
Sex
Female
Sponsor
Kaiser Permanente
Primary completion
Dec 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Depression Symptoms
10.1; 11
PRIMARY
Device-Measured Physical Activity
63.2; 62.3
SECONDARY
Self-reported Physical Activity
13.7; 16.3
SECONDARY
Device-measured Physical Activity
63.2; 62.3
SECONDARY
Depressive Symptoms
7.9; 9.1
SECONDARY
Self-reported Physical Activity
13.7; 16.3

Summary

The purpose of this study is to test whether a web-based (eHealth) exercise intervention for new moms at increased risk for postpartum depression increases physical activity and decreases postpartum depression symptoms.

Eligibility Criteria

Inclusion Criteria

  • KPNC member between 2 and 6 months postpartum
  • Current PHQ-8 score between 10-20 and no current depression diagnosis
  • Delivered baby in KPNC
  • English-speaking
  • Own a smartphone, computer, or TV with internet access
  • Free of a heart condition and a physician recommending medically supervised physical activity
  • Body Mass Index (BMI) between 18.5 and 40 (kg/m2)
  • A baby weighing between 11-22 lbs

Exclusion Criteria

  • Engaged in regular, moderate or vigorous physical activity >90 minutes or more per week
  • Pregnant or planning to become pregnant in the ensuing three months
  • A baby with chronic illness/disorder(s) that prevent participant from holding or lifting him/her
  • Chest pain during physical activity, or has had chest pain within the prior month
  • Taking medication for hypertension or a heart condition
  • Tendency to fall due to syncope or dizziness
  • Orthopedic problems that might be aggravated by physical activity
  • Has exercise-induced asthma
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04414696). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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