N/A N=187 Other

Modifiable Predictors of Neural Vulnerabilities for Obesity

Obesity

Bottom Line

View on ClinicalTrials.gov: NCT04522947 ↗

Enrolled (actual)

187

Serious AEs

0.0%

Results posted

Jan 2026

Primary outcome: Primary: Caudate Activation for Sip Cue — -0.026264341 activation beta value

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Milkshake fMRI (Other)
Age: Adult, Older Adult · 19+ yrs
Sex: All
Sponsor: University of Nebraska Lincoln
Primary completion: Apr 2025

Outcome Measures

Outcome	Result	p-value
PRIMARY Caudate Activation for Sip Cue	-0.026264341	—
PRIMARY Putamen Activation for Sip Cue	-0.020653429	—
PRIMARY Insula Activation for Sip Cue	-0.058804599	—
PRIMARY Caudate Activation for Sip Delivery	-0.01520067	—
PRIMARY Putamen Activation for Sip Delivery	-0.010750489	—
PRIMARY Insula Activation for Sip Delivery	0.084583225	—

Summary

The purpose of this study is to examine patterns of neural activation in a priori selected brain regions associated with reward process during anticipation and delivery of appetizing food stimuli (milkshake sips) among young adults.

Eligibility Criteria

Inclusion Criteria

Age 19 years or older
Previous participation in the Preschool Problem Solving Study OR lived in Lancaster County, NE for at least part of high school

Exclusion Criteria

Contraindications for functional magnetic resonance imaging (fMRI):
metal in body
pregnancy
braces
non-removal piercings
hair extensions
As of 8/13/21, for individuals who were not in the Preschool Problem Solving Study but are invited to participate in the current study because they lived in Lancaster County for at least part of high school, the maximum age for eligibility is 20 years of age.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04522947). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.