N/A
Completed N=59
Mnemonic Strategy Versus Spaced Retrieval Training in Those With Mild Cognitive Impairment
Source: ClinicalTrials.gov NCT04533204 ↗Enrolled (actual)
59
Serious AEs
0.0%
Results posted
Mar 2021
Primary outcomePrimary: Percent of Correct Object Location Associations Assessed up to 1 Month Post-treatment — 80.0; 62.45 percent correct — p=<.001
Summary
This study compared two active cognitive interventions to evaluate whether one improved memory more than the other in patients with mild cognitive impairment. Participants were randomized to either memory strategy training or spaced retrieval training and completed memory tests before and after 3 training sessions. Participants returned 1 month after treatment to see how well they remembered the learned information. Brain scans (functional MRI) were collected before and after the interventions to see if training changed the way brain regions were functioning.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percent of Correct Object Location Associations Assessed up to 1 Month Post-treatment |
80.0; 62.45 | <.001 sig |
| SECONDARY Change in Accuracy (vs. Baseline) on Novel Object Location Associations |
6.1; 7.14 | .004 sig |
Eligibility Criteria
Inclusion Criteria
-Diagnosis of MCI according to Petersen (2004) criteria, right handed
Exclusion Criteria
- Diagnosis of other neurological condition,
- active drug/alcohol abuse/dependence,
- moderate-severe depression or other Axis I diagnoses.
Data sourced from ClinicalTrials.gov (NCT04533204). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.