N/A
Completed N=50
Evaluation of the Effectiveness of Calcium Phosphate Containing Desensitizer on Postoperative Sensitivity
Source: ClinicalTrials.gov NCT04540835 ↗Enrolled (actual)
50
Serious AEs
0.0%
Results posted
Dec 2025
Primary outcomePrimary: Visual Analog Scale (VAS) — 0.4; 1.3 cm on a 10-point Visual Analogue Scale
Summary
In this randomized clinical study, we aim to evaluate the effects of Teethmate Desensitizer on postoperative sensitivity when applied underneath the composite restoration by comparing it with the negative control group.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Visual Analog Scale (VAS) |
0.4; 1.3 | — |
| PRIMARY Numerical Rating Scale (NRS) |
0.1; 0.1 | — |
| SECONDARY Presence of Postoperative Hypersensitivity (Patient-reported at 6 Weeks) |
47; 47 | — |
Eligibility Criteria
Inclusion Criteria
- Accepting to participate
- Being in the age range of 18-65
- Presence of at least 12 teeth in occlusion
- The teeth to be included in the study have natural opposite and aproximal teeth
- The teeth to be included in the study will be vital
- The anterior or posterior teeth to be included in the study, regardless of the deep carious cavity type, have a primary carious lesion that is estimated to be very close to the pulp during cavity preparation but the pulp will not expose (dentin thickness close to the remaining pulp is less than 2 mm)
- In the patient's mouth, one on the right and the other on the left 4., 5. and 6. 2 teeth matching the criteria.
Exclusion Criteria
- Not accepting voluntarily to participate in the study 2- Being younger than 18 years old or over 65 years old 3- Presence of spontaneous toothache or orofacial pain 4- Bruxism 5- Presence of advanced periodontal disease 6- The presence of a serious systemic disease. 7- Worn, cracked or devital teeth with enough material loss to be crowned 8- Presence of lesions in the apical region after radiographic examination 9- Exposure of pulp during cavity preparation 10- Presence of gingival recession 11- Individuals who have taken painkillers, anti-inflammatory and psychotropics in the last two weeks and are currently taking 12- Pregnancy and breastfeeding individuals 13- Individuals who are allergic to the materials to be used
Data sourced from ClinicalTrials.gov (NCT04540835). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.