N/A
N=61
Multi-Component Intervention to Improve Health Outcomes and Quality of Life Among Rural Older Adults Living With HIV
HIV
Bottom Line
View on ClinicalTrials.gov: NCT04549259 ↗Enrolled (actual)
61
Serious AEs
0.0%
Results posted
Jul 2023
Primary outcome: Primary: Proportion of Participants With HIV Viral Load ≥832 Copies/mL (HemaSpot DBS) — 5; 7; 8; 4 Participants — p=.33
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Group-Based Social Support (Behavioral); HIV Stigma Reduction (Behavioral); Strengths-Based Case Management (SBCM) (Behavioral); Personalized Technology Detailing (Behavioral)
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- Medical College of Wisconsin
- Primary completion
- May 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Proportion of Participants With HIV Viral Load ≥832 Copies/mL (HemaSpot DBS) |
5; 7; 8; 4; 6; 6 | .33 |
| PRIMARY Health-Related Quality of Life |
68.54; 64.97; 65.83; 67.51; 66.50; 66.81 | .36 |
| SECONDARY Medication Adherence |
13; 14; 13; 14; 14; 13 | .049 sig |
| SECONDARY Depressive Symptoms |
6.84; 9.33; 8.47; 7.84; 8.08; 8.25 | .24 |
Summary
Engagement in HIV medical care and adherence to HIV medications are both essential in improving health outcomes among people living with HIV (PLH), but PLH living in rural areas-who suffer higher mortality rates than their urban counterparts-can confront multiple barriers to care engagement and adherence, especially as they face the logistical, medical, and social challenges associated with aging. This project will pilot test four intervention components designed to improve care engagement and medication adherence to determine their impact on health outcomes and quality of life among rural, older PLH. The four intervention components, adapted from evidence-based interventions and delivered remotely, are: (1) counselor-facilitated peer social support, (2) HIV stigma reduction, (3) strengths-based case management, and (4) individually-tailored technology use optimization. The investigators hypothesize that components will be acceptable to participants, will be feasible to administer remotely, and will show preliminary impact on (1) the proportion of participants that have viral suppression and (2) health-related quality of life. Results from this study will provide us with tools to improve health outcomes for rural older people living with HIV.
Eligibility Criteria
Inclusion Criteria
- Age 50 years or greater
- Living in a zip code classified as a "Small and Isolated Small Rural Town" area by Rural-Urban Commuting Area Codes (RUCAs), and/or in a county classified as rural based on RUCAs, and/or in a county with a score of .4 or higher on the index of relative rurality (IRR)
- Living in Alabama, Arkansas, Georgia, Kentucky, Mississippi, Missouri, Oklahoma, South Carolina, or Tennessee
- Living with HIV
- Indicates willingness to participate in support groups
- Indicates willingness to self-collect a dried blood spot sample
- Has a telephone at home
- Able to provide informed consent
Exclusion Criteria
- Not meeting eligibility criteria described above
Data sourced from ClinicalTrials.gov (NCT04549259). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.