N/A N=61 Randomized Quadruple-blind Treatment

Concomitant Sensory Stimulation During Therapy to Enhance Hand Functional Recovery Post Stroke

Stroke · Physical Disability

Bottom Line

View on ClinicalTrials.gov: NCT04569123 ↗

Enrolled (actual)

Serious AEs

8.2%

Results posted

Feb 2026

Primary outcome: Primary: Change in Wolf Motor Function Test (WMFT) Movement Time — -4; -9 Seconds (sec)

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: real stimulation (Device); No stimulation (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Medical University of South Carolina
Primary completion: Jan 2025

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Wolf Motor Function Test (WMFT) Movement Time	-4; -9	—
SECONDARY Change in Box and Blocks Test (BBT) Score	2; 4	—
SECONDARY Change in Action Research Arm Test (ARAT) Score	3; 4	—

Summary

The objective of this study is to determine if combining vibration with hand task practice is superior to hand task practice alone.

Eligibility Criteria

Inclusion Criteria

18 years old or older
At least 6 months since stroke
Wolf Motor Function Test (WMFT) total average time >10 seconds
WFMT hand task average time <120 s

Exclusion Criteria

Currently undergoing other upper limb therapy
Change in spasticity medication or upper limb botulinum toxin injection within 3 months prior to or during enrollment
Severe spasticity that limits participation in task practice therapy (e.g., Modified Ashworth Scale=4-5)
Comorbidity affecting the upper limb function such as complete upper extremity deafferentation, orthopaedic conditions limiting motion, premorbid neurologic conditions, premorbid peripheral neuropathy, compromised skin integrity of the wrist due to burn or long-term use of blood thinners, or significant new neurological symptoms
Language barrier or cognitive impairment that precludes following instructions and/or providing consent

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04569123). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.