N/A
N=22
Comparative Abuse Liability Among African American and White Smokers
Tobacco Use Disorder
Bottom Line
View on ClinicalTrials.gov: NCT04646668 ↗Enrolled (actual)
22
Serious AEs
0.0%
Results posted
Jul 2023
Primary outcome: Primary: Nicotine Delivery — 14.13; 6.79; 9.15 ng/mL — p=0.002
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- E-cigarette and Heat not burn (Combination_product)
- Age
- Adult, Older Adult · 21+ yrs
- Sex
- All
- Sponsor
- University of Kansas Medical Center
- Primary completion
- Aug 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Nicotine Delivery |
14.13; 6.79; 9.15 | 0.002 sig |
Summary
The study is a randomized crossover trial. Current smokers will complete a session with each product: usual brand cigarette, e-cigarette, and heat-not-burn. The objective of this survey is to assess for ongoing use of study products and is part of safety monitoring.
Eligibility Criteria
Inclusion Criteria
- Non-Hispanic African American or white/Caucasian,
- ≥21 years old, smoke 5-30 cigarettes per day,
- daily cigarette smoker
- smoked at current rate for at least 6 months
- interested in trying e-cigarettes and heat not burn products
- not interested in or unable/unwilling to quit cigarette smoking
- willing to complete three in-person study visits
- willing to have IV catheter placed
Exclusion Criteria
- Interested in quitting cigarettes in the next 30 days
- use of smoking cessation pharmacotherapy in the past 30 days
- use of non-cigarette tobacco products in the past 30 days
- use of e-cigarettes >5x in lifetime
- use of e-cigarettes ≥4 of the past 30 days
- use of heat not burn products >5x in lifetime
- use of heat not burn products ≥4 of the past 30 days
- weight 10 miles from study site (Fairway CRU)
- current enrollment is a research study or program that aims to alter tobacco use
Data sourced from ClinicalTrials.gov (NCT04646668). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.