N/A
N=12
Automated Reinforcement Management System (ARMS)
Alcohol Use Disorder
Bottom Line
View on ClinicalTrials.gov: NCT04656925 ↗Enrolled (actual)
12
Serious AEs
0.0%
Results posted
Feb 2025
Primary outcome: Primary: Biochemically Measured Change in Alcohol Abstinence. — 347; 615; 209 Number of negative BAC samples by phase.
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Contingency management (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Washington State University
- Primary completion
- Dec 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Biochemically Measured Change in Alcohol Abstinence. |
347; 615; 209 | — |
| SECONDARY Feasibility Indicator of App Usage |
411; 700; 249 | — |
| SECONDARY Treatment Retention |
7.5 | — |
Summary
Alcohol abuse remains a significant cause of preventable morbidity and mortality in the US. Yet only 15% of those with alcohol use disorders receive treatment. Contingency Management (CM) is a cost-effective intervention for drug addiction where individuals are rewarded when they submit biological verification of drug abstinence. The researchers propose to develop an integrated CM system capable of incorporating mobile device input, that would allow them to deliver a CM intervention for problematic drinking to anyone who owns a smartphone. The mobile device input will incorporate ecological momentary assessments (EMA), geospatial mapping, and biomarker-based feedback from a portable measuring device.
Eligibility Criteria
Inclusion Criteria
- Age 18-65 years.
- An Alcohol Use Disorders Identification Test (AUDIT) score of 8 or higher.
- Ability to read and speak English.
- Ability to provide written informed consent.
- Breath alcohol of 0.00 during informed consent.
- Operate a smartphone with an active service provider.
Exclusion Criteria
- Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) alcohol use disorder, severe type.
- Significant risk of dangerous alcohol withdrawal, defined as a history of alcohol detoxification or seizure in the last 12 months and expression of concern by the participant about dangerous withdrawal.
- Diagnosis of a psychotic disorder.
- Lifetime suicide attempt or suicidality in the past year.
- Any other medical or psychiatric condition that would compromise safe participation.
Data sourced from ClinicalTrials.gov (NCT04656925). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.