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N/A N=241 Randomized Treatment

SCS as an Option for Chronic Low Back and/or Leg Pain Instead of Surgery

Chronic Pain

Enrolled (actual)
241
Serious AEs
6.1%
Results posted
May 2024
Primary outcome: Primary: Responder Rate — 51; 5 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
WaveWriter (Device); Conventional Medical Managament (Other)
Age
Adult, Older Adult · 22+ yrs
Sex
All
Sponsor
Boston Scientific Corporation
Primary completion
Aug 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Responder Rate
51; 5
SECONDARY
Change in Disability (Oswestry Disability Index)
-27.5; -7.2

Summary

To evaluate the safety and effectiveness of Spinal Cord Stimulation (SCS) with multiple modalities compared to Conventional Medical Management (CMM) in patients with chronic low back and/or leg pain who have not undergone spinal surgery when using the Boston Scientific WaveWriter SCS Systems.

Eligibility Criteria

Key Inclusion Criteria

  • Chronic low back pain, with or without leg pain, for at least 6 months
  • Received at least 90 days of documented pain management care to address the primary pain complaint, prior to Screening (e.g. medication, physical therapy)
  • If female of childbearing potential: not pregnant, as evidenced by a negative pregnancy test at Screening
  • Subject signed a valid, IRB-approved informed consent form (ICF) provided in English

Key Exclusion Criteria

  • Primary pain complaint of vascular origin (e.g. peripheral vascular disease)
  • Require implantation of lead(s) in the cervical epidural space
  • Significant cognitive impairment at Screening that, in the opinion of the Investigator, would reasonably be expected to impair the study candidate's ability to assess pain intensity
  • Previous failed spinal cord stimulation trial or is already implanted with an active implantable device(s) (e.g. pacemaker, drug pump, implantable pulse generator)
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04676022). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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