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N/A N=107 Randomized Triple-blind Treatment

Project CheckUP: A Brief Behavioral Intervention for Quitline Callers Who Use Marijuana (MJ) and Tobacco

Smoking Cessation · Marijuana Use

Enrolled (actual)
107
Serious AEs
Results posted
Feb 2025
Primary outcome: Primary: Number of Calls Completed — 123; 141 Total number of calls

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Behavioral: Quitline treatment as usual (Behavioral); QL Marijuana Check-Up intervention (QL-MJCU) (Behavioral)
Age
Adult, Older Adult · 21+ yrs
Sex
All
Sponsor
Consumer Wellness Solutions
Primary completion
Dec 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Calls Completed
123; 141
PRIMARY
Tobacco Use
14; 13
PRIMARY
Satisfaction With Treatments
28; 30
PRIMARY
Readiness to Change Marijuana Use
3.3; 2.9
SECONDARY
Biochemical Verification of Tobacco Abstinence
2; 5
SECONDARY
Marijuana Use
23.2; 19.1

Summary

Smoking cigarettes remains the number one preventable cause of death and disease in the US. Smokers who call tobacco quitlines and use marijuana struggle to quit tobacco due to the interactive effects of nicotine and marijuana. A recent study found that 25% of callers to state quitlines said they were using marijuana and 44% of those were interested in quitting or cutting back their marijuana use (in addition to wanting to quit smoking). The investigators propose to develop an integrated intervention for co-users of marijuana and tobacco to be delivered via state-funded quitlines. The investigators will incorporate key elements of an evidence-based brief behavioral intervention called 'The Marijuana Check-Up' into the tobacco quitline treatment. The investigators will evaluate the feasibility, acceptability and preliminary effects of the new intervention in a small randomized pilot study with 100 co-users recruited from four participating state quitlines. Outcomes measured at 3 months post randomization will include tobacco abstinence (biochemically verified) and days used marijuana. The investigators hypothesize that the intervention will: (1) be feasible to deliver (measured by coach treatment fidelity scores); (2) be acceptable to co-users (measured by enrollments into the study and call completion numbers); (3) increase tobacco cessation rates compared with standard quitline treatment; (4) increase co-users motivation to change MJ use; and (5) produce greater reduction in days using MJ compared with standard quitline treatment. The proposed brief behavioral intervention addressing co-use may increase quitline callers' chances of achieving and maintaining tobacco abstinence and increase participants' motivation to reduce marijuana use. As non-medicinal marijuana use becomes common and legal in more states, a low touch phone and web-based intervention for co-users of marijuana and tobacco could improve health outcomes for many. Findings will inform development of scalable public health intervention strategies for co-users easily implemented across quitlines.

Eligibility Criteria

Inclusion Criteria

  • daily use of 5 or more tobacco cigarettes
  • aged 21 and older
  • recruited from participating state quitlines (AK, DC, OR, WA)
  • provides an email address
  • wants to quit tobacco in the next 30 days
  • used cannabis on 9 or more days in the past 30 days

Exclusion Criteria

  • unable to speak and read English
  • have limited access to a telephone
  • pregnant or post-partum (because they are not offered the standard QL program)
  • self-reported schizophrenia
  • all cannabis use is recommended by a doctor or other healthcare professional
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04737772). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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