N/A Completed N=70 Health Services Research

Disease Management Platform for Heart Failure (DMP-HF)

Heart Failure

Source: ClinicalTrials.gov NCT04782973 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Mar 2025

Primary outcomePrimary: Feasibility of Implementation — 51; 51; 51 Participants

Summary

AMAZE™ is a disease management platform (DMP) designed to educate patients about heart failure, help engage them in healthy behaviors and assist them in taking their medications as prescribed. This study will assess whether the AMAZE™ smartphone-based application ("app") can help heart failure patients take better care of themselves after discharge from an inpatient heart failure admission at Massachusetts General Hospital (MGH). The primary objective is to demonstrate feasibility and perceived value of the AMAZE™ platform in clinical practice. The study will also explore whether the use of the AMAZE™ platform for 60 days post-discharge leads to a reduction in hospital readmission, emergency department, urgent care and unexpected ambulatory care visits. The impact of the AMAZE™ platform on participant reported quality of life outcomes and perception of overall medical care will also be examined.

Outcome Measures

Outcome	Result	p-value
PRIMARY Feasibility of Implementation	51; 51; 51	—
PRIMARY Perceived Value of Disease Management Platform	6; 7; 6; 6; 6; 6	—
SECONDARY Disease Management Platform Engagement	22; 44	—
SECONDARY Health Status Change With Use of Disease Management Platform	2; 2; 5; 6; 18; 9	—

Eligibility Criteria

Inclusion Criteria

Adults (>21 years) admitted to MGH Cardiology services (Ellison 10 and 11) with a primary diagnosis of heart failure [HFrEF(<40%), HFmEF(40-49%) HFpEF(≥50%)] (or to BWH Cardiology services for BWH EHR-based controls)

Has a smartphone or iPad and is willing to enter health metrics into DMP App and email willing to use for the study

Access to the internet

Established or with plan to establish primary cardiologist at MGH (or at BWH for BWH EHR-based controls)

Discharged home or to self-care (with or without home services)

Exclusion Criteria

Moderate or severe cognitive impairment

Non-English-speaking

Palliative management only (comfort measures)

Does not own a smartphone or iPad (not considered for EHR-based controls)

Incarcerated

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04782973). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.