N/A
Completed N=51
Marijuana Use, Strength Training, and Alcohol Consumption (MUSTAC) Study
Source: ClinicalTrials.gov NCT04791917 ↗Enrolled (actual)
51
Serious AEs
0.0%
Results posted
Jul 2023
Primary outcomePrimary: Alcohol Demand: Breakpoint — -6.00; -2.07; -1.81; -1.09 dollars/drink — p=.26
Summary
Self-medication of pain by consuming alcohol and marijuana is common. However, the research regarding pain as a determinant for alcohol and marijuana use has relied on laboratory pain induction paradigms with limited clinical relevance. The study will assess demand for alcohol and marijuana before and after delayed onset muscle soreness (DOMS) induction in co-users. This will provide a clinically relevant, but time-limited, model for the effects of musculoskeletal pain on demand.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Alcohol Demand: Breakpoint |
-6.00; -2.07; -1.81; -1.09 | .26 |
| PRIMARY Alcohol Demand: Omax |
-.255; -.089; -.03; -.168 | .11 |
| PRIMARY Alcohol Demand: Pmax |
-.19; -.080; .0054; -.11 | .17 |
| PRIMARY Alcohol Demand: Essential Value |
-.18; -.072; -.24; -.073 | .91 |
| PRIMARY Cannabis Demand: Intensity |
-.019; .12; -.070; -.10 | .14 |
| PRIMARY Cannabis Demand: Breakpoint |
.40; -.14; -.36; -.80 | .83 |
| PRIMARY Cannabis Demand: Omax |
.019; -.010; -.001; -.10 | .15 |
| PRIMARY Cannabis Demand: Pmax |
.0005; -.043; .014; -.10 | .24 |
| PRIMARY Cannabis Demand: Essential Value |
-.061; .059; -.032; .15 | .97 |
| PRIMARY Alcohol Demand: Intensity |
-.094; .047; .0958; -.07 | .04 sig |
Eligibility Criteria
Inclusion Criteria
- Age ≥ 21 years;
- English-speaking
- Self-identify as White/Caucasian or Black/African American
- Own a smartphone with cellular/data plan
- Regularly co-use alcohol and smoked marijuana as indicated by scores of ≥3 on item 1 of the CUDIT-R and AUDIT.
- Willing and able to give informed consent
Exclusion Criteria
- Participation in biceps-specific conditioning program in the past 6 months*
- Self-reported wrist/hand, elbow, or shoulder pain the past 3 months
- Chronic medical condition that may affect pain perception (e.g. diabetes, fibromyalgia, headaches)
- Self-reported kidney dysfunction, muscle damage, or major psychiatric disorder
- Medical marijuana prescription
- Consumption of marijuana using only non-inhalational methods (e.g. edibles, tinctures, or cannabidiol oil)
- Score of ≥ 10 on Patient Health Questionnaire-9 (moderate depression)
- Women who are pregnant, trying to become pregnant, or breastfeeding
Data sourced from ClinicalTrials.gov (NCT04791917). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.