N/A
Completed N=106
Addressing Insufficient PAP Use in Older Veterans
Source: ClinicalTrials.gov NCT04868682 ↗Enrolled (actual)
106
Serious AEs
6.6%
Results posted
Nov 2025
Primary outcomePrimary: PAP Adherence — 2.16; 0.87 hours per night — p=.0001
Summary
Obstructive sleep apnea (OSA) is a common problem among middle-aged and older Veterans that is associated with poor nighttime sleep, more daytime sleepiness, poor functioning and worse quality of life. The recommended therapy for most patients with OSA is positive airway pressure (PAP) therapy; however, over time many patients prescribed PAP therapy no longer use it regularly. This study will test the effects of an behavioral treatment specifically designed for middle-aged and older Veterans who have stopped using their PAP device, or are not using it regularly.
Eligible Veterans who are enrolled into the study will receive a baseline assessment that includes questionnaires about sleep, health, and quality of life. After completing the baseline assessment, participants will be randomly assigned to one of two groups. Both groups will meet individually with a "sleep coach" for 5 session over 8 weeks, then they will be contacted by the sleep coach monthly by telephone for up to 6 months. Participants will complete follow-up assessments immediately after the fifth education session and again at 6-months and 12-months.
If successful, this approach has the potential to improve sleep, function and quality of life in middle-aged and older Veterans with OSA.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY PAP Adherence |
2.16; 0.87 | .0001 sig |
| SECONDARY Sleep Quality |
7.72; 8.01 | 0.378 |
| SECONDARY Daytime Sleepiness |
6.11; 7.59 | <0.001 sig |
| SECONDARY Sleep-related Function |
14.65; 15.67 | 0.865 |
Eligibility Criteria
Inclusion Criteria
- Diagnosis of moderate to severe obstructive sleep apnea (apnea hypopnea index [AHI] > or = 15)
- Previously prescribed positive airway pressure (PAP) therapy
- Insufficient PAP use (defined as no PAP use over the past 30 days)
Exclusion Criteria
- Severe psychopathology (e.g., active psychosis) that precludes participation in the study
- Severe unstable medical illness that precludes participation in the study
- Significant cognitive impairment
Data sourced from ClinicalTrials.gov (NCT04868682). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.