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Sleep apnea

Part of Sleep Disorders, Intrinsic

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for sleep apnea

48 trials tracked for sleep apnea: 1 in phase 3 or 4.

48Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 3 1 Phase 2 7 Phase 1 4 Other / NA 36
  1. Phase 3 Telemedicine Interventions for Obstructive Sleep Apnea (OSA) Completed
  2. Phase 2 Positional Therapy After Stroke Completed
  3. Phase 2 Chronic Evaluation of Respicardia Therapy Completed
  4. Phase 2 A Pilot Study of the Effects on Sleep Disordered Breathing (SDB) When Using the Drug Liraglutide for 4 Weeks Completed
  5. Phase 2 A Novel Pharmacological Therapy for Obstructive Sleep Apnea Completed
  6. Phase 2 A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults Completed
Show 42 more trials
  1. Phase 2 Dimethyl Fumarate for Obstructive Sleep Apnea Completed
  2. Phase 2 Effects of Treating Obstructive Sleep Apnea in Epilepsy Completed
  3. Phase 1 Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease? Completed
  4. Phase 1 Effects of Suvorexant in Participants With Obstructive Sleep Apnea (MK-4305-036) Completed
  5. Phase 1 Pharmacodynamics and Efficacy of MK-7288 in Adults With Sleep Apnea (MK-7288-010) Completed
  6. Phase 1 Oxytocin on HR in Sleep Apnea Patient Completed
  7. N/A TatchSleep as a Tool to Aid in Sleep Apnea Analysis Completed
  8. N/A A Multi-Center Study to Assess the Performance of Saturation Patterns. Completed
  9. N/A High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients Completed
  10. N/A Hyperglycemic Profiles in Obstructive Sleep Apnea: Effects of PAP Therapy Completed
  11. N/A Mapping for Acute Transvenous Phrenic Nerve Stimulation Study Completed
  12. N/A Advancing Understanding of Transportation Options Completed
  13. N/A Comparison of Breathing Event Detection by a Continuous Positive Airway Pressure Device to Clinical Polysomnography Completed
  14. N/A Non-Inferiority Study of the FRESCA Mask Versus Existing CPAP Mask for Treatment of Obstructive Sleep Apnea Completed
  15. N/A Atrial Fibrillation Recurrence in Sleep Apnea Completed
  16. N/A Determinants of Age Related Breathing Instability During Non-Rapid-Eye-Movement (NREM) Sleep Completed
  17. N/A Treating Sleep Apnea in Women Veterans Completed
  18. N/A Diagnosis and Treatment of Sleep Apnea in the Acute Exacerbation of Heart Failure Completed
  19. N/A Comparison of Sleep Apnea Assessment Strategies to Maximize TBI Rehabilitation Participation and Outcome Completed
  20. N/A Positive Airway Pressure for the Treatment of Asthma Completed
  21. N/A The Role of Oxidative Stress in the Cardiovascular Consequences of Sleep Apnea Completed
  22. N/A A Validation Study of the NightOwl PAT-based Home Sleep Apnea Test Completed
  23. N/A Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea Completed
  24. N/A Non-Inferiority Study of the FRESCA Airbox Positive Airway Pressure System Completed
  25. N/A Effects of Continuous Positive Airway Pressure (CPAP) on Glucose Metabolism Completed
  26. N/A Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment Completed
  27. N/A Clinical Validation of New Commercial Sleep Monitoring Devices Completed
  28. N/A Effect of Treatment of Sleep Apnea in Patients With Paroxysmal Atrial Fibrillation Completed
  29. N/A Radiofrequency Ablation for Multi-level Obstructive Sleep Apnea: A Single-arm, Multicenter Study Completed
  30. N/A Tri Staple Technology Stapler Used in Gastric Bypass Completed
  31. N/A The Effects of Treating Obese and Lean Patients With Sleep Apnea Completed
  32. N/A Sleep Apnoea Breathing Record Exploratory Study (SABRES) Completed
  33. N/A Influence of Sleep Apnea on Risk of Atrial Fibrillation Completed
  34. N/A Estimating Apnea Phenotypes From Polysomnography: Oxygen Completed
  35. N/A Alice PDx User/Validation Extended Trial Completed
  36. N/A Modified AutoSet Device vs Existing AutoSet Device, the Assessment of Efficacy and Subjective Comfort of the Treatment. Completed
  37. N/A Long QT Syndrome and Sleep Apnea Completed
  38. N/A The Treatment of Insomnia Comorbid With Sleep Disordered Breathing Using Armodafinil and/or Cognitive Behavioral Therapy for Insomnia Completed
  39. N/A Addressing Insufficient PAP Use in Older Veterans Completed
  40. N/A Study Will Test the Theory That Training With the Facial-Flex Exercise Device Will Improve Snoring in Patients Completed
  41. N/A Effective Treatment of Sleep Apnea in Prediabetes to Reduce Cardiometabolic Risk Completed
  42. N/A Apnea Hypopnea Index Severity Versus Head Position During Sleep Completed

Showing the 48 most-cited and recently-updated of 48 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Sleep Disorders, Intrinsic

Related studies from across the Sleep Disorders, Intrinsic family.

DaVinci Single-Port transoral robotic surgery is feasible across multiple indications including oncology and sleep apnea
Oncology Meta-analysis
DaVinci Single-Port transoral robotic surgery is feasible across multiple indications including oncology and sleep apnea Single-Port Robot Shows Promise for Sleep Apnea Surgery
This systematic review and meta-analysis of 479 patients evaluates the feasibility of DaVinci Single-Port (SP) transoral robotic surgery (TO…
A new analysis finds single-port robotic surgery for sleep apnea is feasible, with short operating times and low blood loss.
1 in 7 COPD patients decline or discontinue long-term PAP therapy, meta-analysis finds
Pulmonology & Critical Care Meta-analysis
1 in 7 COPD patients decline or discontinue long-term PAP therapy, meta-analysis finds 1 in 7 COPD patients decline or stop breathing therapy
This systematic review and meta-analysis of patients with COPD newly prescribed long-term noninvasive positive airway pressure (PAP) therapy…
A new analysis finds 14% of COPD patients decline or stop long-term breathing therapy, often within six weeks.
NIV with total face mask managed acute respiratory failure in two patients with Madelung's disease and COVID-19 pneumonia
Rheumatology Sys. Review
NIV with total face mask managed acute respiratory failure in two patients with Madelung's disease and COVID-19 pneumonia Non-invasive ventilation may help patients with Madelung's disease and respiratory failure
This case series describes non-invasive ventilation using a total face mask in two patients with Madelung's disease who experienced acute re…
A small case series suggests non-invasive ventilation can manage acute respiratory failure in patients with Madelung's disease, though more …
Renal denervation combined with pulmonary vein isolation increases freedom from atrial fibrillation risk in resistant hypertension patients
Cardiology Meta-analysis
Renal denervation combined with pulmonary vein isolation increases freedom from atrial fibrillation risk in resistant hypertension patients Renal denervation may help resistant hypertension patients with heart issues
This systematic review and meta-analysis evaluated renal denervation in patients with resistant hypertension. The pooled analysis included 8…
A meta-analysis suggests renal denervation improves heart and sleep markers in patients with resistant hypertension, though larger trials ar…
Radiotherapy and chemotherapy show no clear link to obstructive sleep apnea in head and neck cancer patients
ENT (Otolaryngology) Meta-analysis
Radiotherapy and chemotherapy show no clear link to obstructive sleep apnea in head and neck cancer patients Radiation for head and neck cancer may raise sleep apnea risk
This scoping review with exploratory meta-analysis of 13 studies found no significant association between radiotherapy or chemotherapy and i…
A review of 13 studies suggests a possible link between radiation for head and neck cancer and mild sleep apnea, but the evidence is too wea…
Non-surgical weight loss reduces AHI by 11.10 in adults with obstructive sleep apnoea
Primary Care & Family Medicine Meta-analysis
Non-surgical weight loss reduces AHI by 11.10 in adults with obstructive sleep apnoea Non-surgical weight loss lowers sleep apnea severity and blood pressure in adults
This systematic review and meta-analysis evaluated non-surgical weight loss interventions in adults with obstructive sleep apnoea. The poole…
Non-surgical weight loss significantly reduced sleep apnea severity and blood pressure in adults, though long-term results remain uncertain.
MAD shows modest BP benefit over CPAP in OSA patients
Neurology Meta-analysis
MAD shows modest BP benefit over CPAP in OSA patients Mandibular advancement devices lower blood pressure better than CPAP for some patients
A meta-analysis found mandibular advancement devices slightly outperform CPAP for lowering daytime blood pressure in obstructive sleep apnea…
For patients with obstructive sleep apnea, a new analysis shows mandibular advancement devices reduced daytime blood pressure more than CPAP…
Delayed arousal timing links to higher mortality in sleep apnea patients
Pulmonology & Critical Care Meta-analysis
Delayed arousal timing links to higher mortality in sleep apnea patients Timing of breathing pauses predicts death risk in obstructive sleep apnea
A meta-analysis found that each one-second delay in post-apnea arousal peak time was associated with increased all-cause and cardiovascular …
New analysis shows how late a breathing pause wakes you up predicts higher death risk for men with obstructive sleep apnea.
Meta-analysis links moderate-to-severe obstructive sleep apnea to higher metabolic syndrome risk in patients
ENT (Otolaryngology) Meta-analysis
Meta-analysis links moderate-to-severe obstructive sleep apnea to higher metabolic syndrome risk in patients Patients with worse sleep apnea face higher risks for diabetes and high blood pressure compared to those with milder cases
This meta-analysis evaluated the association between obstructive sleep apnea syndrome (OSAS) severity and metabolic syndrome risk. The poole…
A large review of over ten thousand patients shows that worse sleep apnea greatly increases the chance of getting metabolic syndrome, high b…
Meta-analysis finds obstructive sleep apnea associated with sarcopenia in adults
ENT (Otolaryngology) Meta-analysis
Meta-analysis finds obstructive sleep apnea associated with sarcopenia in adults Sleep apnea linked to higher muscle loss risk in many adult groups studied
This meta-analysis of 13,331 participants found a significant association between obstructive sleep apnea syndrome and sarcopenia. The assoc…
A large review of 13,331 adults found that sleep apnea is connected to losing muscle mass. The link is especially strong in older people and…
Systematic review and meta-analysis shows Twin-Block appliance reduces AHI in pediatric obstructive sleep apnea
Pediatrics Meta-analysis
Systematic review and meta-analysis shows Twin-Block appliance reduces AHI in pediatric obstructive sleep apnea New analysis shows Twin-Block appliance helps children with sleep breathing problems reduce bad sleep scores significantly
This systematic review and meta-analysis evaluated the Twin-Block appliance for pediatric obstructive sleep apnea. Data from 259 patients ac…
A review of eight studies found that a special mouth appliance called Twin-Block helps children with sleep apnea. It lowers breathing stoppa…
CPAP Most Effective for Apnea-Hypopnea Index, GLP-1 RAs Improve Weight in OSA
Diabetes & Endocrinology Meta-analysis
CPAP Most Effective for Apnea-Hypopnea Index, GLP-1 RAs Improve Weight in OSA CPAP and weight-loss drugs show different benefits for sleep apnea patients
This network meta-analysis of 3964 adults with obstructive sleep apnea found that CPAP produced the largest reduction in apnea-hypopnea inde…
A large analysis found CPAP best for breathing control, while weight-loss drugs improved body weight and blood sugar levels in sleep apnea p…