N/A
N=10
Pediatric Language and Memory Mapping in Refractory Epilepsy Using Magnetoencephalography
Epilepsy
Bottom Line
View on ClinicalTrials.gov: NCT04888637 ↗Enrolled (actual)
10
Serious AEs
0.0%
Results posted
Feb 2025
Primary outcome: Primary: Completed MEG — 1 participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Baseline MEG Test (Diagnostic_test); Receptive Language Task (Behavioral); Memory Task (Behavioral)
- Age
- Pediatric, Adult · 8+ yrs
- Sex
- All
- Sponsor
- University of Arkansas
- Primary completion
- Jul 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Completed MEG |
1 | — |
Summary
This is a pilot research study where language and working memory tasks will be used to study brain activities from children with epilepsy. Specifically for language assessment, a well-known MEG language protocol will be used and novel signal processing techniques will be applied. A widely utilized paradigm will be used to study memory function and adapt signal-processing techniques from previous literature for the processing and analysis of MEG signals collected during memory task. No treatment/intervention will be performed or evaluated in this pilot research study.
Eligibility Criteria
Inclusion Criteria
- 8 to 21 years old
- Drug-resistant focal epilepsy
- Enrolled in the Arkansas Children's Neuroscience Center Comprehensive Epilepsy Program
- Under evaluation for resective surgery
- English speakers. This is not a treatment/intervention study.
Exclusion Criteria
- Previous resective surgery for epilepsy
- Presence of progressive neurodegenerative disorders
- Presence of significant magnetic artifacts; electronic, magnetic or metallic implants (e.g. pins, screws, shrapnel remains, surgical clips, artificial heart valves, cochlear implants, vascular stents pacemakers); or permanent make-up or tattoos made with metallic dyes
- Presence of seizures within 24 hours of the MEG
- Use of sedation during the MEG acquisition
- Inability to be in a seated or supine position during the tasks
- Major medical disorders (e.g. HIV, cancer)
- Significant visual or auditory disabilities
- Physical disabilities that interfere with accomplishment of study tasks (when applicable)
- Claustrophobia, or fear of cramped or confined spaces
- Pregnancy or suspected pregnancy
- Any condition that the investigator feels might put the patient at risk
Data sourced from ClinicalTrials.gov (NCT04888637). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.