N/A
Completed N=37
Precision Pharmacotherapy Smoking Cessation Program
Source: ClinicalTrials.gov NCT04897607 ↗Enrolled (actual)
37
Serious AEs
2.7%
Results posted
Mar 2023
Primary outcomePrimary: Number of Participants Who Achieve Smoking Cessation — 1; 1 Participants
Summary
The purpose of this study is to determine the benefits of a personalized treatment approach, compared to a non-personalized treatment approach, for smoking cessation. In other words, this study will help us know if recommending a specific medication to individual smokers will make it easier to quit smoking than simply offering an option of medications. The specific recommendation for a medication will be based on a test that measures how quickly a smoker breaks down, or metabolizes, nicotine.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants Who Achieve Smoking Cessation |
1; 1 | — |
| SECONDARY Percentage of Participants Who Reported Using Smoking Cessation Medication (1-week) |
11; 14 | — |
| SECONDARY Percentage of Participants Who Reported Using Smoking Cessation Medication (4-week) |
4; 6 | — |
| SECONDARY Percentage of Participants Who Reported Use of a Smoking Medication That Matched Their NMR Profile |
5; 11 | — |
Eligibility Criteria
Inclusion Criteria
- current smoker (5+ cigarettes/day)
- patient at the Helen F. Graham Cancer Center & Research Institute (ChristianaCare) lung/thoracic clinic
Exclusion Criteria
- use of non-cigarette tobacco products or smoking cessation treatment
- psychiatric or other medical contraindications to receiving smoking cessation medication
- no telephone
- medical instability
- inability to communicate in English
- unable to consent due to mental status
- estimated life expectancy of <6 months
- not a Delaware resident
- pregnancy
Data sourced from ClinicalTrials.gov (NCT04897607). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.