N/A
Completed N=20
Overcoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility Study
Source: ClinicalTrials.gov NCT04978350 ↗Enrolled (actual)
20
Serious AEs
—
Results posted
Jul 2025
Primary outcomePrimary: Acceptability of Workbook Assessed Through Likert Score Scale — 10; 3 Participants
Summary
The investigators will evaluate the feasibility of an intervention to improve Lynch syndrome cascade screening uptake. The investigators will conduct a pilot study among 15 patients diagnosed with Lynch Syndrome and 5 genetic counselors to assess the feasibility and intermediate outcomes of an educational workbook containing exercises and resources to improve family communication among individuals with Lynch Syndrome and first-degree relatives of individuals with Lynch Syndrome.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Acceptability of Workbook Assessed Through Likert Score Scale |
10; 3 | — |
Eligibility Criteria
Inclusion Criteria
- Patients must have been diagnosed with Lynch Syndrome within the last 365 days.
- Patients and genetic counselors must be age 18 or older.
- Patients must be receiving care from genetic counselors at Ohio State University Comprehensive Cancer Center or at UNC Health System.
- Genetic counselors must provide Lynch Syndrome counseling for patient participants at Ohio State University Comprehensive Cancer Center or at UNC Health System.
- Patients and genetic counselors must be able to speak and read in English.
- Patients and genetic counselors must review informed consent documents and provide verbal consent to participate in the study.
Exclusion Criteria: There are no exclusion criteria for study participants.
Data sourced from ClinicalTrials.gov (NCT04978350). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.