Colonoscopic Surveillance in Lynch Syndrome Linked to Lower Mortality but Not Reduced Cancer Incidence
Colonoscopies Save Lives in High-Risk Patients
This observational cohort study of 4732 MMR-carriers in the English NHS found that colonoscopic surveillance was associated with decreased C…
You’ve just turned 35. Your mom had colon cancer at 42.
Meta-analysis finds 3.2% prevalence of germline MMR mutations in patients with upper tract urothelial carcinoma
Study finds 3.2% of upper tract urothelial cancer patients have inherited DNA repair mutations
A systematic review and meta-analysis of 14 studies including 2378 patients with upper tract urothelial carcinoma (UTUC) found a pooled prev…
About 3% of upper tract urothelial cancer patients carry inherited DNA repair mutations that link their cancer to Lynch syndrome and affect …
Case series identifies MSH2 variants in three families suspected of Lynch syndrome
Genetic study identifies Lynch syndrome variants in three families with colon cancer history
A case series of three families with suspected Lynch syndrome used whole-exome sequencing and immunohistochemistry to characterize MSH2 vari…
Genetic testing found new disease-causing variants in three families with colon cancer history, offering clues for precision screening and g…