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N/A N=103 Randomized Single-blind Treatment

Delaware Physical Exercise and Activity for Knee Osteoarthritis

Knee Osteoarthritis

Enrolled (actual)
103
Serious AEs
2.9%
Results posted
Jan 2025
Primary outcome: Primary: Change in Moderate-to-vigorous Intensity Physical Activity — 0.7; 2.6; 2.7; 1.6 min/day of MVPA

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Intervention (Behavioral); Control (Behavioral)
Age
Adult, Older Adult · 45+ yrs
Sex
All
Sponsor
University of Delaware
Primary completion
Jun 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Moderate-to-vigorous Intensity Physical Activity
0.7; 2.6; 2.7; 1.6
SECONDARY
Change in Treatment Beliefs of Physical Therapy: Positive
1.0; 0.4; 0.4; -0.6
SECONDARY
Change in Treatment Beliefs of Physical Exercise: Positive
1.3; 0.0; 1.2; -0.4
SECONDARY
Change in Light Intensity Physical Activity (LPA)
3.8; 2.6; -3.4; -13.1
SECONDARY
Change in Steps/Day
517.5; 259.0; 269.3; -206.5
SECONDARY
Change in Treatment Beliefs of Physical Therapy: Negative
-0.6; 1.0; -1.0; 0.5
SECONDARY
Change in Treatment Beliefs of Physical Exercise: Negative
-0.6; 1.0; -1.0; 0.5

Summary

The objective of this project is to examine the efficacy of an innovative Telehealth Physical Therapy (PT) program for adults with knee osteoarthritis (OA) to increase physical activity over 12 weeks in adults with knee OA compared to a control group receiving web-based resources about knee OA. One hundred individuals with knee osteoarthritis (OA), who are over the age of 45, and are also looking to move more, will be randomized into a brief or expanded intervention group. The control includes an online, guided video orientation from a physical therapist to web resources for strengthening exercises, physical activity, and pain management strategies for knee OA. The intervention includes up to 5 online consultations with a physical therapist over a 12-week period who will prescribe strengthening exercises, physical activity goals, and pain management strategies for knee OA.

Eligibility Criteria

Inclusion Criteria

  • meet the National Institute for Health and Care Excellence Osteoarthritis (NICE) clinical criteria:
  • being at least 45 years of age;
  • having activity-related joint pain;
  • having morning stiffness ≤ 30 minutes;
  • have a history of knee pain for at least 12 weeks;
  • are interested in becoming more physically active;
  • have either a cell phone or laptop/desktop computer with broadband internet connection and working email address; and
  • are able to commit to the study for 12 weeks and willing to wear physical activity monitors
  • live in the contiguous United States
  • comfortable participating in a program delivered in English
  • is able to safely participate in a moderate-intensity exercise as determined by a pre-exercise screen questionnaire.

Exclusion Criteria

  • regularly exercise more than 60 minutes/week; or
  • has a scheduled knee or hip joint replacement; or
  • has had physical therapy for knee OA in the past 6 months; or
  • participated in a strength training program for the lower extremities in the past 6 months.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04980300). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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