N/A
N=809
Randomized Controlled Trial of Game Changers
HIV Prevention
Bottom Line
View on ClinicalTrials.gov: NCT05098015 ↗Enrolled (actual)
809
Serious AEs
0.3%
Results posted
Jan 2026
Primary outcome: Primary: HIV Testing — 71.60; 71.61 percentage of alters — p=0.95
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Game Changers (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- RAND
- Primary completion
- Oct 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY HIV Testing |
71.60; 71.61 | 0.95 |
| PRIMARY Condom Use |
18.04; 13.15 | 0.16 |
| SECONDARY Internalized HIV Stigma |
1.62; 2.06 | <.001 sig |
| SECONDARY HIV Prevention Advocacy |
3.53; 2.85 | <.001 sig |
Summary
The study is a randomized controlled trial (RCT) of Game Changers, an 8-session peer-led group intervention that aims to empower and mobilize people living with HIV (PLWH) to be agents for HIV prevention in their social networks.
Eligibility Criteria
Inclusion Criteria
- age 18 years and older
- HIV-positive
- in HIV care at The Infectious DIseases Institute for at least one year
Exclusion Criteria
- Participated in the prior pilot study of the intervention.
- Has significant cognitive impairment
- Health status is not sufficiently stable to reliably complete 18 month study.
- Does not speak Luganda fluently (index participant); English or Luganda fluently (social network participant)
- spouse/partner or household member are enrolled as index participant in the study
Data sourced from ClinicalTrials.gov (NCT05098015). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.