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N/A Completed N=245 Randomized Single-blind Supportive Care

Transmission of Coronavirus Disease 2019 (COVID19) in Crowded Environments

Source: ClinicalTrials.gov NCT05119348 ↗
Enrolled (actual)
245
Serious AEs
0.0%
Results posted
Aug 2024
Primary outcomePrimary: SARS-CoV-2 Infection — 4; 2 Participants

Summary

South Africa recorded it's first coronavirus disease 2019 (COVID19) case on March 5, 2020. In response to the COVID19 outbreak World Health Organisation recommendations, South Africa implemented non-pharmaceutical recommendations. The major risk mitigation factors recommended by World Health Organisation and others - physical distancing and hygiene - are extremely difficult to implement in much of Africa. The investigators will conduct a randomised controlled trial to investigate the effect of an infection mitigation intervention to assess the effect on household transmission of severe acute respiratory syndrome (SARS) coronavirus (CoV) 2 in household settings with an index patient diagnosed SARS-CoV-2 positive.

Outcome Measures

OutcomeResultp-value
PRIMARY
SARS-CoV-2 Infection
4; 2
SECONDARY
COVID19 Symptoms
11; 9

Eligibility Criteria

Inclusion Criteria

  • recently diagnosed SARS-CoV-2 positive
  • Individual >12 years
  • Able to give assent if 18 years
  • Self-isolating at home at the time of COVID diagnosis

Exclusion Criteria

  • <12 years
  • Unable to give consent
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05119348). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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