N/A
Completed N=76
Neural Basis of Sensory and Motor Learning: Functional Connections
Basic Science
Source: ClinicalTrials.gov NCT05124301 ↗
Enrolled (actual)
76
Serious AEs
0.0%
Results posted
Jan 2026
Primary outcomePrimary: Resting-state PMv-M1 Functional Connectivity (Fisher Z-transformed Correlation) — 0.64 unitless (Fisher z-score)
Summary
The purpose of this study is to understand how the sensory and motor areas of the brain work together to keep a person's hand movements accurate (sensorimotor learning). The investigators hope this information may be useful one day to improve rehabilitation techniques in patients with brain lesions.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Resting-state PMv-M1 Functional Connectivity (Fisher Z-transformed Correlation) |
0.64 | — |
| PRIMARY Weighting of Vision vs. Proprioception |
43.9 | 0.0022 sig |
Eligibility Criteria
Inclusion Criteria
- Ages of 18-45 years old
- Right-handed.
- Free of Covid symptoms in week preceding testing.
Exclusion Criteria
- metallic, mechanical, or magnetic implants;
- are claustrophobic, or are unable to remain still for long periods of time;
- use an intra-uterine device (IUD) whos MR compatibility has not been established.
- Women who are pregnant or think they might be pregnant will also be excluded, as effects of fMRI on the unborn are not known.
- People who have a BMI over 30 will be excluded as it may be uncomfortable or impossible to lay in the MRI scanner and reach the button box.
- Potential subjects will be excluded if they have any neurological disorders, or orthopedic or pain conditions in the upper limbs.
- Investigators will also exclude subjects who do not have normal vision, or corrected-to-normal vision with contacts, or the imaging center does not have a pair of MRI compatible glasses that fits their prescription.
- investigators will invite subjects to reschedule if they have any of the common Covid symptoms within the last week and if they haven't been fully vaccinated or obtained a negative Covid test within the past 4 days. If they don't believe they can meet these criteria on another date, they will be excluded.
- After giving their consent, participants may be excluded during the study if they are unable to perform the tasks or follow instructions.
Data sourced from ClinicalTrials.gov (NCT05124301). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.