N/A N=203 Potency and Precision Investigation
Depression, Anxiety
Primary: Working Alliance Inventory-Short Revised (WAI-SR), Total Scale — 3.63; 3.25; 3.95; 3.61 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=17 Effect of a Basic Skin Care Product on the Structural Strength of the Skin
Healthy Skin
Primary: Blistering Time (Full Blister) — 63; 54; 65; 62 Minutes
N/A N=14 Team Science (The Liver Health Study)
Steatotic Liver Disease of Mixed Origin (MetALD)
Primary: Proportion Screened With Alcohol Intake and Weight-related Risks for Metabolism and Alcohol-associated Liver Disease — 26 Participants
N/A N=5 Biological Response of Trauma Patients to Standard Trauma Resuscitation Therapy
Hemorrhagic Shock
Primary: Biological Response as Characterized by Selected Cytokines, Specifically Tumor Necrosis Factor Alpha (TNFα), Interleukin One (IL-1β), and Interleukin Six (IL-6).
N/A N=1,951 SciBase International Melanoma Pivotal Study
Malignant Melanoma
Primary: SciBase Sensitivity and Specificity — 96.6; 31.4 Percentage of total lesions — p=<0.0001
N/A N=30 Probe Configuration and Time-Temperature Dose Ranging for Understanding of Skin Lesion Effects
Histological Response of Tissue to Cold
Primary: Biological Tissue Response
N/A N=160 Neurobehavioral Plasticity to Regular Sugar-Sweetened Beverage Intake: An fMRI Experiment
Obesity · Weight Gain
Primary: Change in Voxel-wise Blood Oxygen Level Dependent (BOLD) Including Outliers Using Functional Magnetic Resonance Imaging (fMRI) of Brain Activation Signals in Response to…
N/A N=40 Proficiency Based Robotics Training Curriculum: Skill Acquisition & Transferability of Skills to Live Porcine Models
Medical Students Naive to Surgical Robotics
Primary: Global Evaluative Assessment of Robotic Skills (GEARS) Scale — 15.25; 15.37 units on a scale
N/A N=90 Exploration of Blood Flow Regulation to Bone in Humans
Bone Blood Flow Regulation
Primary: Tibial Blood Perfusion — 0.54; -1.47; 0.43; 2.08 μM (concentration)
N/A N=110 Mitochondrial Stress, Brain Imaging, and Epigenetics
Mitochondrial Diseases
Primary: Average TSST-induced Elevation in Cortisol — 37.44; 33.86; 42.83; 45.42 ng*min/mL
Phase 1 N=13 Induced Sputum Study (0000-065)
Asthma
Primary: Hour 24 Fold Change From Period Baseline in Interleukin-5 (IL-5) Protein Concentration (pg/mL) — 2.57; 0.87 pg/mL — p=0.011
Phase 1 N=21 Investigation of the Safety and Tolerability of BSCT (Anti-nf-P2X7) 10% Ointment
Carcinoma, Basal Cell (BCC)
Primary: Incidence of Treatment-Emergent Adverse Events (Safety and Tolerability) — 1; 12 participants
N/A N=225 Redox Determinants of Severe Asthma (a Substudy of the Severe Asthma Research Program)
Asthma
Primary: Exhaled Nitric Oxide at Baseline and Over the Observational Period — 15.1; 9.9; 13.7; 8.6 parts per billion
Phase 2 N=30 Stress Response and Neurodevelopmental Outcome After Cardiac Surgery Utilizing CPB in Children: A Prospective, Double Blinded and Randomized Study
Congenital Heart Disease
Primary: Change in Cytokine Levels — 4.38; 4.2; 3.98; 3.85 picograms per milliliter
Early Phase 1 N=138 Drugs Brain and Behavior (DDP)
Stimulant Use
Primary: Change in SUbjective Effects as Assessed by Score on "Feel Drug", "Feel High", "Like Drug", and "Want More" Sub-scales of Drug Effects Questionnaire (DEQ). — 19.2; 57.8…
N/A N=82 Patient Response to Spinal Manipulation
Low Back Pain
Primary: Patient-Centered Outcome Measurement Mean Change After 6 Weeks (VAS, RMDQ) — 20.1; 4.8 units on a scale (see description above)
N/A N=360 Hydration Factor Study for the Stayhealthy BC3
Body Composition
Primary: Estimated Body Fat % for Children Aged 10-17 Years Old — 18.4; 18.8 Percent body fat — p=0.87
N/A N=637 Transforming Research and Clinical Knowledge in TBI Pilot
Traumatic Brain Injury
Primary: Glasgow Outcome Scale Extended (GOSE) — 7; 5 Glasgow Outcome Scale Extended (GOSE)
N/A N=36 Brain Function and Decision-Making
Behavior, Social · Psychology, Social · Social Interaction
Primary: Change in Prefrontal Cortex Brain Activity Assessed by fMRI — -0.002; 0.015 Percent BOLD Signal Change
N/A N=71 Musculoskeletal Plasticity After Spinal Cord Injury
Spinal Cord Injuries
Primary: Acute Gene Regulation: MSTN — 5.49; 4.76 arbitrary units — p=<0.001
Phase 4 N=30 Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia
Tetraplegia · Hypothermia · Mild Cognitive Impairment
Primary: Change in Core Body Temperature — -0.24; -0.97; NA; 0.79 °C — p=<0.001
N/A N=180 The BrainHealth Project - Pilot Study
Healthy
Primary: The BrainHealth Index — 54 score on a scale — p=<0.001
N/A N=32 Utilizing Exhaled Breathe Condensate Collection to Study Ion Regulation in Cystic Fibrosis
Cystic Fibrosis · Healthy
Primary: Exhaled Sodium (mmol/L) — 2.58; 2.24; 1.97; 2.11 mmol/L
Phase 1 N=9 This Study in Healthy Men and Women Tests How the Body Takes up BI 409306
Healthy
Primary: Area Under the Concentration-time Curve of BI 409306 and Stable Labelled Isotope BI 409306 (C-13/N-15) Over the Time Interval From 0 Extrapolated to Infinity (AUC0-∞)…
N/A N=878 Disseminating Organizational SBI Services at Trauma Centers
Alcohol Abuse · Alcohol Dependence
Primary: Number of Participants With Hazardous Drinking — 292; 309; 201; 223 Participants
N/A N=7 The Impact of the Physiological Response to Sugar on Brain Activity and Behavior
Food Preferences · Appetitive Behavior
Primary: Change in Preference- Subjective Liking Ratings for Each Beverage on a Scale — -12.8; -12.0; -12.6 units on a scale
N/A N=5 Quantitative Characterization of Safe Irrigation for Ventricular Shunt Catheters
Hydrocephaly
Primary: To Demonstrate That the Flusher Can be Primed, Connected, and Activated in a Sterile Clinical Setting Per the Instructions for Use by the Treating Investigator . — 4; 4…
Early Phase 1 N=27 Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype
Primary Ciliary Dyskinesia
Primary: Baseline MCC (Ave60Clr; Average Clearance Over 60 Minutes) — 1.4; -1.1; 7.3 percent clearance — p=0.002
N/A N=21 Absorptive Clearance in the Cystic Fibrosis Airway
Cystic Fibrosis
Primary: Absorptive Clearance Rate — 42; 32 percentage of DTPA absoprtion per hour
Phase 4 N=155 Baseline Oral Health Study: UnCoVer the Connections to General Health
Cardiovascular Diseases · Diabetes Type 2
Primary: Impact of Treatment on Change in Oral Health Measures — 0.186; 0.190 millimeters (probing depth difference) — p=0.957