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N/A N=13 Treatment

Assessment of Laryngopharyngeal Sensation in Adductor Spasmodic Dysphonia

Spasmodic Dysphonia · Adductor Spasmodic Dysphonia · Voice Disorders

Bottom Line

View on ClinicalTrials.gov: NCT05158179 ↗
Enrolled (actual)
13
Serious AEs
0.0%
Results posted
Jan 2024
Primary outcome: Primary: Laryngeal Adductor Reflex — 13 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Sensation testing (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of California, San Francisco
Primary completion
Apr 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Laryngeal Adductor Reflex		 13 —
SECONDARY
Perceptual Strength of Sensation on a 1-10 Numerical Rating Scale (NRS)		 4.6 —

Summary

Study investigators have completed a study testing laryngopharyngeal sensation at specific laryngopharyngeal subsites using a novel buckling force aesthesiometer in a series of 22 healthy adults at this institution. Investigators would like to use the same device apparatus to evaluate laryngopharyngeal sensation in patients with laryngopharyngeal disorders, such as adductor spasmodic dysphonia. This study will use a tested laryngopharyngeal aesthesiometer to examine laryngeal sensation using calibrated tactile stimuli to determine differences in somatotopic perceptual strength maps of laryngopharyngeal structures between patients with laryngopharyngeal disorders and healthy controls.

Eligibility Criteria

Inclusion Criteria

  • Adductor spasmodic dysphonia (can have co-diagnosis of essential tremor)
  • received Botox injection more than 2 weeks ago

Exclusion Criteria

  • excessive gagging
  • active smoker
  • non-Botox responsive
  • abductor spasmodic dysphonia exclusively
  • essential tremor diagnosis exclusively
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05158179). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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