N/A N=20 rTMS in Spasmodic Dysphonia
Spasmodic Dysphonia · Laryngeal Dystonia
Primary: Adverse Response to rTMS — 0; 0 Participants
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N/A N=6 Thalamic Deep Brain Stimulation for Spasmodic Dysphonia- DEBUSSY Trial
Spasmodic Dysphonia · Laryngeal Dystonia · Deep Brain Stimulation
Primary: Unified Spasmodic Dysphonia Rating Scale (USDRS) — 2.5; 3.75 units on a scale — p=0.025
N/A N=42 Laryngeal Vibration for Spasmodic Dysphonia
Spasmodic Dysphonia
Primary: Voice Assessment During First Visit — 0.045; 0.17; 0.13; -0.47 decibel
Phase 3 N=32 Spasmodic Dysphonia Pain
Spasmodic Dysphonia
Primary: Pain Experienced — 2; 2; 2 score on a scale
Phase 2 N=53 Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response
Spasmodic Dysphonia · Voice Tremor
Primary: Number of Participants Who Reported Positive Effects. — 17; 20 Participants
Phase 3 N=108 Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor
Spasmodic Dysphonia · Voice Tremor
Primary: Symptom Severity — 28.0; 18.6; 14.2; 12.3 score on a scale — p=0.01
Phase 2 N=22 DaxibotulinumtoxinA Injection for Treatment of Adductor Spasmodic Dysphonia
Adductor Spasmodic Dysphonia · Voice Disorders · Spasmodic Dysphonia
Primary: Our Primary Outcome is the Difference in VHI-10 Score at 30 Days After Injection With DAXI. — 17.81 units on a scale — p=<0.001
N/A N=24 The Effects of Respiratory Training on Voice
Muscle Tension Dysphonia
Primary: Post Training Lung Volume Initiation — 21.07; 27.04 % vital capacity relative to rest level — p=<0.0005
N/A N=13 Assessment of Laryngopharyngeal Sensation in Adductor Spasmodic Dysphonia
Spasmodic Dysphonia · Adductor Spasmodic Dysphonia · Voice Disorders
Primary: Laryngeal Adductor Reflex — 13 Participants
N/A N=36 Voice Treatment for Parkinson's Disease
Idiopathic Parkinson Disease
Primary: Treatment-related Changes in Vocal Intensity Will be Assessed Using Acoustic Analysis. — 3; 3; 0.26 Decibels
N/A N=30 Evaluating the Feasibility of Acapella® Choice as a Dysphonia Treatment
Muscle Tension Dysphonia · Vocal Fold Palsy · Vocal Cord Paralysis
Primary: Change in Baseline Cepstral/Spectral Index of Dysphonia (CSID) — 1.22; 4.45; 4.56; 3.13 score on a scale
N/A N=8 Essential Voice Tremor: A Study of Botulinum Toxin Treatment and Injection Augmentation
Essential Tremor
Primary: Vocal Tremor Scoring System (VTSS) — 0.57; 0.57; 1; 0.43 units on a scale
N/A N=20 Respiratory Muscle Strength Training in Presbyphonia
Presbylarynx
Primary: Post-Treatment Mean in Voice Handicap Index Score — 15.00; 15.75; 18.50 score on a scale — p=0.041
Phase 4 N=18 Propranolol and Botulinum Toxin for Essential Vocal Tremor
Essential Vocal Tremor · Essential Voice Tremor · Essential Tremor
Primary: Change in Quality of Life in Essential Tremor (QUEST) Questionnaire Score — 39.41; 29.50; 23.60 units on a scale
N/A N=30 MyoVoice to Restore Natural, Hands-free Communication to Individuals With Vocal Impairments
Rehabilitation of Speech and Language Disorders · Speech Disorders · Speech, Alaryngeal
Primary: Pitch Recognition Accuracy — 7.70 Percent agreement to reference pitch
N/A N=104 An RCT of a Telemedicine Intervention for Hypokinetic Dysarthria in PD
Parkinson's Disease
Primary: Change in Speech Intelligibility at 6 Months — 0.25; -4.78 score on a scale — p=0.13
N/A N=58 Voice Therapy With a Semi-occluded Vocal Tract
Voice Disorders
Primary: (Supra)Glottic Activity: Amplitude of Vibration — 37.7; 32.5; 28.8; 37.1 percentage
N/A N=20 Evaluation of Intensive Language Therapy
Parkinson's Disease
Primary: Velocity in Gait — 1.2; 1.2; 1.2; .8 meter per second — p=.05
N/A N=11 Efficacy of a Semi-occluded Mask in the Treatment of Patients With Voice Disorders
Voice and Resonance Disorders · Vocal Fold Polyp · Vocal Cord Cyst
Primary: Change From Baseline in VHI-10 Score After 4 Sessions of Voice Therapy — 7 score on a scale — p=.0076
N/A N=9 rTMS and Botulinum Toxin in Primary Cervical Dystonia
Primary Cervical Dystonia · Dystonia
Primary: Dystonia Severity as Assessed by the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) — 13; 17 scores on a scale
N/A N=17 Swallowing Training in Parkinson's Disease
Parkinson's Disease · Deglutition Disorders · Voice Disorders
Primary: Oropharyngeal Swallowing Score — 22.15; 21.93 Scores on a scale
Phase 3 N=243 Dysport® Adult Upper Limb Spasticity
Nervous System Disorders
Primary: Change From Baseline in MAS Score in the Primary Targeted Muscle Group (PTMG) — -0.3; -1.2; -1.4 units on a scale
N/A N=6 Video Assisted Speech Technology to Enhance Motor Planning for Speech
Autism Spectrum Disorder · Apraxia of Speech
Primary: Change in Mean Length of Utterance (MLU) — 0.5387; 0.2987 Morphemes per utterance — p=<0.555
N/A N=31 Controlled Phonation and Vocal Rest Programs After Acute Vocal Exertion in Healthy Adults
Healthy
Primary: Phonation Threshold Pressure — 5.41; 5.08; 6.39; 6.33 cmH20 — p=<0.001
Phase 2 N=18 Dysport for the Treatment of OMD
Oral Dystonia · Tardive Dystonia
Primary: Mean Global Dystonia Rating Scale Score as Measured by Blinded Rater — 3.80; 3.57; 3.71 units on a scale
N/A N=6 Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)
Apraxia of Speech · Aphasia, Acquired · Speech Disorders
Primary: Speech Production: Percent Change in Treated Items Immediately Post Treatment — 59; 66 % change
N/A N=12 The Passy Muir Swallowing Self Training Device
Oropharyngeal Dysphagia
Primary: Change in Swallow Frequency 30 Hz — 0.512 Change in swallows/min — p=0.218
N/A N=8 Identification of Optimal Stimulation Site for Cervical Dystonia Symptoms: An Exploratory Study
Cervical Dystonia · Spasmodic Torticollis
Primary: Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) — -3.0; 0.25; -2.9; -1.5 units on a scale
N/A N=435 Application of Ideal Binary Masking to Disordered Speech
Hearing Loss, Sensorineural · Dysarthria
Primary: Percent Correct Speech Intelligibility — 69; 63 percentage of words correctly reported
N/A N=5 Thalamic Deep Brain Stimulation for Secondary Dystonia in Children and Young Adults
Dystonia
Primary: Change From Baseline in Burke-Fahn-Marsden Dystonia Rating Scale — 14.7 change in points on a scale