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N/A N=636 Randomized Prevention

Addressing the Continuum of Care Among High-risk Thai Men

HIV/AIDS · STD

Enrolled (actual)
636
Serious AEs
0.0%
Results posted
Dec 2025
Primary outcome: Primary: Prevalence of HIV Testing in the Past 6 Months Among YMSM at Baseline — 92; 48 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
HUG-M+ (Behavioral)
Age
Pediatric, Adult · 15+ yrs
Sex
Male
Sponsor
Mahidol University
Primary completion
Dec 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Prevalence of HIV Testing in the Past 6 Months Among YMSM at Baseline
92; 48
PRIMARY
Prevalence of HIV Testing in the Past 6 Months Among YMSM at 6 Months
114; 80
PRIMARY
Prevalence of HIV Testing in the Past 6 Months Among YMSM at 12 Months
104; 98
PRIMARY
Prevalence of HIV Testing in the Past 6 Months Among YMSM at 18 Months
96; 96
PRIMARY
Prevalence of HIV Testing in the Past 6 Months Among YMSM at 24 Months
61; 77
PRIMARY
Prevalence of Condomless Anal Sex in the Past 6 Months Among YMSM at Baseline
56; 63
PRIMARY
Prevalence of Condomless Anal Sex in the Past 6 Months Among YMSM at 6 Months
37; 42
PRIMARY
Prevalence of Condomless Anal Sex in the Past 6 Months Among YMSM at 12 Months
24; 40
PRIMARY
Prevalence of Condomless Anal Sex in the Past 6 Months Among YMSM at 18 Months
29; 39
PRIMARY
Prevalence of Condomless Anal Sex in the Past 6 Months Among YMSM at 24 Months
25; 37

Summary

Young Thai men who have sex with men (YMSM) are at high risk for HIV. However, the Thailand National HIV Strategy does not adequately cover HIV prevention for YMSM using specific methods relevant to them, and instead uses a one-size-fits all approach. Partnering with the Thailand Ministry of Public Health (MOPH), the proposed study seeks to finalize, implement and evaluate a multicomponent, multi-level, community mobilization, combination intervention (HUG-M+) to address the entire Continuum of Prevention and Care. The investigators propose to test the efficacy of this approach by conducting research in two Northeastern Thai cities, one randomized to the intervention condition, which will receive HUG-M+ and the other to the control condition, where standard of care will be provided. If HUG-M+ is found to be efficacious, it might be scaled up, with the support of the MOPH, to other regions in Thailand, elsewhere in Asia and the US.

Eligibility Criteria

Inclusion Criteria

  • Age 15-29 years at cohort baseline
  • Self-reported male gender
  • Self-reported having had anal sex with another man in the past 12 months
  • Speak, read and write Thai
  • Thai citizenship
  • Resident of the assessment city for the next 2 years (live, work or go to school)

Exclusion Criteria

  • Do not consent to urine testing or anal swab
  • Not willing to give contact information for follow-up assessments
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05161689). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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