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N/A N=48 Treatment

Total30 Sphere Contact Lenses

Contact Lens Complication · Dry Eye

Enrolled (actual)
48
Serious AEs
0.0%
Results posted
Dec 2022
Primary outcome: Primary: Visual Analog Scale (VAS) Ocular Comfort — 36.66; 38.06; 33.68; 39.36 units on a scale — p=0.07

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Total30 Sphere Contact Lenses (Device)
Age
Adult · 18+ yrs
Sex
All
Sponsor
University of Alabama at Birmingham
Primary completion
Jul 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Visual Analog Scale (VAS) Ocular Comfort
36.66; 38.06; 33.68; 39.36; 31.26; 33.84 0.07

Summary

The purpose of this study is to map comfort over the full wear day in established, asymptomatic, soft CL wearers who are refit in Total30 Sphere CLs.

Eligibility Criteria

Inclusion Criteria

  • Current contact lens wearers who have 20/20 visual acuity or better
  • Minimally symptomatic as based upon Contact Lens Dry Eye Questionnaire scores (≤10)
  • Astigmatism better than or equal to 0.50 D in each eye
  • Must have regularly worn 2 week or monthly contact lenses within the past 6 months
  • Must provide a glasses prescription that is is less than 3 years old
  • Willing to start wearing their contact lenses between 6:00 AM and 8:00 AM and wear their contact lenses until 11:00 PM each day

Exclusion Criteria

  • Past or Current hard CL use
  • Any known systemic health conditions that are thought to alter tear film physiology
  • History of viral eye disease
  • History of ocular surgery
  • History of severe ocular trauma
  • Active ocular infection or inflammation
  • Currently using isotretinoin-derivatives
  • Currently using ocular medications
  • Currently using rewetting drops or artificial tear
  • Pregnant or breast feeding
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05183022). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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