N/A N=61 Evaluation of Comfilcon A and Senofilcon A Lenses
Myopia
Primary: Subjective Responses for Comfort Rated on a 0-100 Visual Scale. — 86; 87; 89; 91 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=30 Impact of Soft Contact Lenses on Lid-Parallel Conjunctival Folds
Lid-Parallel Conjunctival Folds
Primary: Lid-Parallel Conjunctival Folds (LIPCOF) — 1.95; 1.75; 1.70; 1.40 Score
N/A N=24 Open Eye Corneal Swelling With Daily Disposable Contact Lenses and no Lens Wear
Corneal Swelling
Primary: Percentage Change From Baseline of Corneal Swelling 8 Hours Post Fit — 0.07; -0.02; 0.14; -0.06 percentage of change from baseline
N/A N=37 Endothelial Bleb Response With Toric Lenses
Ametropia
Primary: Endothelial Bleb Areas on Cornea: Session A- Open Eye — 0.1; 2.0; 0.2; 2.1 Percent Difference of Bleb Area
N/A N=14 Contact Lens Insertion and Removal in a Senior Subject Demographic
Visual Acuity
Primary: Overall Success Rate of Insertion and Removal of a Contact Lens — 85.7 Percentage of eyes
Phase 4 N=218 Daily Wear Corneal Infiltrative Event Study
Myopia · Hyperopia · Corneal Infiltrative Events
Primary: Number of Participants Developing a Corneal Inflammatory Event (CIE) — 6; 7 participants
N/A N=191 Handling Comparison Between Two Contact Lens Types
Presbyopia
Primary: Overall Lens Handling Using the Contact Lens User Experience(CLUE) TM Questionnaire. — 53.44; 55.81; 61.70; 60.23 units on a scale
N/A N=16 Evaluating Contact Lens Optics
Myopia
Primary: Visual Performance — 0.23; 0.38 logMAR
N/A N=25 Contact Lens Adaptation in Neophytes
Contact Lens Comfort
Primary: Between-Group Difference in Eye Comfort as Measured by the Ocular Surface Disease Index (OSDI) — 10.8; 16.3 Units on a Scale — p=0.83
N/A N=60 Dailies Total 1 Sphere Contact Lenses
Dry Eye · Contact Lens Complication
Primary: Visual Analog Scale (VAS) Contact Lenses Comfort Scores — 44 Score on a scale — p=<0.001
N/A N=60 Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear
Contact Lens-induced Corneal Fluorescein Staining
Primary: The Primary Outcome Measure Will be Corneal Epithelial Dye Diffusion Rate in Nanometers Per Second, for the Test and Control Eyes. — 0.0567; 0.0583 nanometers per second
N/A N=45 Clinical Comparison of Two Marketed Reusable Cosmetic Contact Lenses
Visual Acuity
Primary: Visual Performance — 0.40; 0.38; -0.09; -0.10 logMAR Units
N/A N=33 Clinical Biocompatibility Evaluation of Contact Lens Coatings
Refractive Errors · Ametropia
Primary: Average Percent Area of Solution-related Corneal Staining — 7.01; 12.82; 13.54; 7.58 percentage of area
N/A N=236 Clinical and Laboratory Evaluation of 3 Contact Lenses With 4 Contact Lens Solutions
Contact Lens Solutions
Primary: Overall Comfort Score (Senofilcon A Lens) — 64.42; 59.73; 63.75; 63.47 units on a scale
Phase 4 N=50 Corneal and Conjunctival Sensitivity and Staining Study
Myopia · Hyperopia
Primary: Corneal Sensitivity — 26.9; 25.5 percent CO2
N/A N=38 Central Corneal Swelling With Silicone Hydrogel Materials
Corneal Swelling
Primary: Central Corneal Swelling — 542.2; 542.4; 544.3 um
N/A N=46 Treating Contact Lens Discomfort With Orthokeratology
Dry Eye · Contact Lens Complication
Primary: Contact Lens Comfort — 22.03; 9.83 Units on a Scale — p=<0.001
N/A N=26 Evaluation of Contact Lenses and Conjunctival Staining in Normal Patients
Conjunctival Staining
Primary: Mean Circumlimbal Conjunctival Staining Score — 6.39; 5.55; 5.68 Units on a scale
N/A N=62 Contact Lens Comfort Relative to Meibomian Gland Status
Meibomian Gland Dysfunction
Primary: Comfort as Measured by the Contact Lens Users Experience Questionnaire (CLUE) — 58.67 units on a scale
N/A N=65 Ocular Characteristics in Contact Lens and Spectacle Wear
Visual Acuity
Primary: Non-Invasive Break Up Time (NIBUT) or Non-Invasive Keratograph Break Up Time (NIKBUT) — 8.28; 11.10 Seconds
N/A N=113 Clinical Evaluation of 3 Contact Lens Materials With 3 Solution Types
Visual Acuity, Slit Lamp Biomicroscopy (Corneal Staining Assessment)
Primary: Subject Comfort — 92.4; 92.4; 92.0; 63.0 Units on a scale
N/A N=72 Ocular Comfort and the "Aging" Lens (ERBIUM)
Refractive Error
Primary: Phase 3: Ocular Comfort, Lens Age 1 Day, Hour 1 — 76; 88 Units on a scale
Phase 4 N=46 Evaluation of Systane Complete for the Treatment of Contact Lens Discomfort
Contact Lens Discomfort · Dry Eye
Primary: Contact Lens Symptoms — 20.41; 18.92; 12.86; 17.92 Score on a Scale
N/A N=105 Clinical Long-Term Evaluation of Approved and Investigational Contact Lenses
Visual Disorders
Primary: Proportion of Eyes Grade 3 or Higher SLF — 0; 0 Proporiton of Subject Eyes
Phase 4 N=20 The Impact of Contact Lens Coefficient of Friction (CoF) on the Development of Lid Wiper Epitheliopathy (LWE)
Lid Wiper Epitheliopathy
Primary: Lid Wiper Epitheliopathy — 0.63; 0.25 score on a scale
N/A N=20 Ocular Comfort and OCT Observation of Post Lens Clearance and Ocular Tissue Compression
Ocular Comfort
Primary: Final Comfort — 87.6; 87.9 Units on a scale
N/A N=20 Effects of Multifocal Contact Lens on Ocular Tissue
Visual Acuity
Primary: Upper Eye Lid Margin Staining — 1.96 mm^2
N/A N=130 Evaluation of Approved and Investigational Contact Lenses
Visual Acuity
Primary: Overall Comfort — 67.509; 61.185 Units on a Scale
N/A N=446 Clinical Evaluation of the Long-Term Effects of Contact Lens Care Systems
Myopia
Primary: Average Daily Wear Time — 13.57; 13.30 Hours
Phase 3 N=246 Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear
Ametropia
Primary: Best Corrected Visual Acuity — 0.65; 1.33; 98.06; 98.67 Percentage of Participants