N/A
Completed N=34
Microelectrodes in Epilepsy
Source: ClinicalTrials.gov NCT05200455 ↗Enrolled (actual)
34
Serious AEs
6.7%
Results posted
Sep 2022
Primary outcomePrimary: Feasibility of Microelectrode Technology to Isolate Place Responsive Neurons in the Human Hippocampus as Measured by the Number of Place Responsive Neurons. — 79 place responsive neurons
Summary
The purpose of this study is to test microelectrodes in intracranial monitoring to see if they will provide novel information on the epileptic potential of the implanted brain tissue. A secondary objective is to investigate the activity of single neurons during specific cognitive tasks.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Feasibility of Microelectrode Technology to Isolate Place Responsive Neurons in the Human Hippocampus as Measured by the Number of Place Responsive Neurons. |
79 | — |
| SECONDARY How Precise the Frequencies (Alpha, Beta, Delta, Theta, Gamma, and High-gamma) of Neural Brain Activity Predict the Speed of the Participant at Performing the Cognitive Task (Accuracy Measured in Percentage). |
0.477; 0.490; 0.440; 0.444; 0.362; 0.382 | — |
Eligibility Criteria
Inclusion Criteria
- 18-65 year old
- male or female
- right or left handed
- IQ>70
- medically refractory focal epilepsy requiring intracranial EEG for pre-surgical evaluation deemed medically necessary
- no contraindications to intracranial electrode study
- able and willing to participate in research
Exclusion Criteria
- does not meet the inclusion criteria
Data sourced from ClinicalTrials.gov (NCT05200455). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.