N/A
N=186
Responses to Regulated E-Cigarette Advertisements
Tobacco Use
Bottom Line
View on ClinicalTrials.gov: NCT05207033 ↗Enrolled (actual)
186
Serious AEs
0.0%
Results posted
May 2025
Primary outcome: Primary: Tobacco Use at 1 Month — 5; 5 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Regulated ad condition (Other); Unregulated ad condition (Other)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Massachusetts, Worcester
- Primary completion
- Jun 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Tobacco Use at 1 Month |
5; 5 | — |
| PRIMARY Tobacco Use at 3 Months |
3; 2 | — |
| PRIMARY Tobacco Use at 6 Months |
1; 2 | — |
| PRIMARY Perceived Severity of Using E-Cigarettes at 1 Month |
4.41; 4.46 | — |
| PRIMARY Perceived Severity of Using E-Cigarettes at 3 Months |
4.41; 4.36 | — |
| PRIMARY Perceived Severity of Using E-Cigarettes at 6 Months |
4.48; 4.48 | — |
| PRIMARY Motivation to Avoid E-Cigarettes at 1 Month |
7.66; 8.05 | — |
| PRIMARY Motivation to Avoid E-Cigarettes at 3 Months |
7.74; 8.02 | — |
| PRIMARY Motivation to Avoid E-Cigarettes at 6 Months |
7.87; 8.00 | — |
| PRIMARY Behavioral Intentions at 1 Month |
3.23; 3.32 | — |
| PRIMARY Behavioral Intentions at 3 Months |
3.19; 3.37 | — |
| PRIMARY Behavioral Intentions at 6 Months |
3.24; 3.20 | — |
| PRIMARY Number of Participants With Biochemical Verification of Tobacco Use at 1 Month |
0; 1 | — |
| PRIMARY Number of Participants With Biochemical Verification of Tobacco Use at 3 Months |
1; 2 | — |
| PRIMARY Number of Participants With Biochemical Verification of Tobacco Use at 6 Months |
0; 3 | — |
Summary
While conventional cigarette use continues to decline among youth and young adults, e-cigarette (EC) use is on the rise. Specifically, the investigators will conduct a randomized control trial (RCT) where young adults are randomized to one of two conditions: 1) a regulated ad environment, with high impact EC ad features removed or 2) an unregulated ad environment, with high impact EC ad features left intact. Participants will view EC ads embedded in an online magazine 24 times over the course of 6 months. EC experimentation and sustained use will be the primary outcome of interest.
Eligibility Criteria
Inclusion Criteria
- 18 to 26 years old,
- fluent in English (earn a score of at least 4 on the Rapid Estimate of Adult Literacy in Medicine)
- biochemically confirmed abstinence of alcohol (BrAC=.00) and combusted tobacco or marijuana exhaled carbon monoxide (eCO<6 parts per million) at time of visit,
- reporting never trying an e-cigarette, not even a puff OR reporting tried and e-cigarette in the past but not in the past 30 days. Susceptibility to EC use, will be determined using the Susceptibility to Use Tobacco Products questionnaire, with only those identifying anything besides "no curiosity/interest" to all three susceptibility questions as susceptible users.
Exclusion Criteria
- Out of age range 18-26 years
- Use of an e-cigarette in past 30 days
- Pregnant women
Data sourced from ClinicalTrials.gov (NCT05207033). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.