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N/A Completed N=141 Randomized Supportive Care

Advance Care Planning in the Emergency Department

Heart Failure · Metastatic cancer · Chronic Kidney Disease Requiring Chronic Dialysis · Chronic Obstructive Pulmonary Disease
Source: ClinicalTrials.gov NCT05209880 ↗
Enrolled (actual)
141
Serious AEs
0.0%
Results posted
May 2025
Primary outcomePrimary: Change in Advance Care Planning (ACP) Engagement With Clinicians at One Month — 2.84; 2.87; 3.37; 3.32 score on a scale — p=0.5835

Summary

This is a two-armed, parallel-design, pre-/post-intervention assessment study. The investigators will conduct a randomized controlled trial for ED GOAL on a cohort of 120 older adults with serious illness to collect patient-centered outcomes and determine preliminary efficacy on increasing advance care planning engagement (self-reported and/or in the electronic medical record) one month after leaving the emergency department. The investigators will also conduct qualitative interviews with participants of ED GOAL.

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Advance Care Planning (ACP) Engagement With Clinicians at One Month
2.84; 2.87; 3.37; 3.32 0.5835
SECONDARY
Feeling Heard and Understood Survey
7; 6; 4; 6; 12; 12
SECONDARY
Quality of Communication Survey
8.80; 8.53; 8.65; 8.61; 8.03; 8.07
SECONDARY
Healthcare Utilization
0; 0; 0; 0; 2; 2
SECONDARY
Mortality
1; 1; 4; 4
SECONDARY
Qualitative Benefits and Obstacles of Advance Care Planning (ACP) Conversations After ED GOAL
16; 7; 17; 3; 15; 17
SECONDARY
Electronic Medical Record Documentation of Advance Care Planning (ACP) Conversations
0; 0; 10; 5; 17; 7
SECONDARY
Change in Advance Care Planning (ACP) Engagement With Clinicians at Three Months
2.84; 2.87; 3.56; 3.55
SECONDARY
Change in Advance Care Planning (ACP) Engagement With Clinicians at Six Months
2.84; 2.87; 3.73; 3.70
SECONDARY
Participant-reported Completion of Advance Care Planning (ACP) Conversations
12; 5; 33; 28; 7; 5

Eligibility Criteria

Inclusion Criteria

  • ≥50 years of age AND ≥1 Serious illness* OR ED clinician would not be surprised if patient died in the next 12 months (a validated prognostic sign)
  • English-speaking
  • Capacity to consent
  • Patient with mild cognitive impairment or mild dementia with capacity to consent (requires a caregiver/study partner to enroll)
  • Caregiver of patient with moderate/severe dementia with capacity to consent

(*) NYHA Stage III/IV congestive heart failure, chronic obstructive lung disease on home oxygen, chronic kidney disease on dialysis, or metastatic solid tumor cancer. In addition, patients with NYHA Stage I/II congestive heart failure, chronic obstructive lung disease not on home oxygen, chronic kidney disease not on dialysis will be included if recent hospitalization in the last 12 months exists.

Exclusion Criteria

  • Acute physical or emotional distress
  • Determined by treating or study clinician not to be appropriate
  • Clearly documented goals for medical care** (Unless the treating or study clinician recommends that the intervention is clinically indicated)
  • Delirium (assessed using 3D-CAM)
  • Already enrolled in this study
  • Unable/unwilling to schedule the follow-ups on the calendar
  • Receive both the outpatient care for serious illness and primary care outside of the Mass General Brigham health system

(**)e.g., MOLST, medical order for life-sustaining treatment, documented serious illness conversations in clinician notes within the last 3 months, etc.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05209880). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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