N/A
N=24
Acupuncture in Myasthenia Gravis (AcuMG)
Myasthenia Gravis
Bottom Line
View on ClinicalTrials.gov: NCT05230082 ↗Enrolled (actual)
24
Serious AEs
2.1%
Results posted
Sep 2025
Primary outcome: Primary: To Determine the Effect of Acupuncture on Quality of Life in Patients With MG — 10.8; 9.4; 3.6; 8.3 score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Acupuncture (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- HealthPartners Institute
- Primary completion
- Apr 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY To Determine the Effect of Acupuncture on Quality of Life in Patients With MG |
10.8; 9.4; 3.6; 8.3 | — |
| SECONDARY To Determine the Effect of Acupuncture on Activities of Daily Living in Patients With MG |
5.0; 3.6; 2.3; 3.5 | — |
Summary
The purpose of the study is to determine the effect acupuncture treatment on individuals with a diagnosis of Myasthenia Gravis (MG). A total of 20 people with MG will be enrolled in this study to receive acupuncture treatment 2 times a week for 12 weeks. Participants will be randomized into two groups: 1) Immediate start and 2) Delayed start (12 weeks). The delayed start group will act as a control group for the first 12 weeks, but then receive acupuncture treatment for 12 weeks. It is hypothesized that patients with MG who receive acupuncture treatment will have improved quality of life and activities of daily living compared to no treatment.
Eligibility Criteria
Inclusion Criteria
- Ability to provide and provision of signed and dated informed consent form
- Age 18-80
- Diagnosis of MG
Exclusion Criteria
- Non-English speaking
- Participation in acupuncture treatment outside of the study, while enrolled
- History of any other serious neurological, psychiatric, chronic pain disorders, or seizures
- History of bleeding diathesis, other bleeding disorders, or syncope with needle puncture
- History of cardiac arrhythmia or current pacemaker, neurostimulator, or other implanted stimulation device
- Recent or active substance use disorder
- Women who are currently pregnant, lactating, or planning to become pregnant during the study
- Any other medical conditions that could affect their ability to participate in acupuncture treatments for the study duration (as determined by study investigators)
- Active participation or past participation ≤3 months in any other interventional study.
- Unwilling to participate in all study related activities
Data sourced from ClinicalTrials.gov (NCT05230082). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.