N/A Completed N=23 Randomized Double-blind Other

Red and Processed Meat Effects on the Metabolome and Microbiome

Controlled Feeding Trial · Healthy Eating Index · Red Meat · Meat

Source: ClinicalTrials.gov NCT05274906 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Sep 2024

Primary outcomePrimary: Test the Effects of Red and Processed Meat on Aqueous Biomarkers of the Blood Metabolome — 0.87; 0.60; 3.48; 5.66 ratio of day 21 to day 0

Summary

This controlled feeding trial will identify biomarkers in the metabolome and microbiome that may differ when consuming a healthy diet with or without red and processed meat.

Outcome Measures

Outcome	Result	p-value
PRIMARY Test the Effects of Red and Processed Meat on Aqueous Biomarkers of the Blood Metabolome	0.87; 0.60; 3.48; 5.66; 0.99; 0.88	—
PRIMARY Test the Effects of Red and Processed Meat on Lipid Biomarkers of the Blood Metabolome	1.09; 0.98; 1.11; 0.97; 0.89; 0.80	—
PRIMARY Test the Effects of Red and Processed Meat on Biomarkers on the Urine Metabolome	0.99; 1.09; 1.54; 2.18; 1.16; 1.24	—
PRIMARY Test the Effects of Red and Processed Meat on Gut Microbiome	0.99; 1.00	—
PRIMARY Test the Effects of Red and Processed Meat on Fecal Bacterial Functional Genes	0.54; 0.24; 0.07; 0.19; 0.23; 0.11	—

Eligibility Criteria

Inclusion Criteria

Healthy adult,
18-50 years of age,
able to read, speak, and understand English, and
willing to come to the Fred Hutchinson Cancer Research Center campus twice weekly during study

Exclusion Criteria

known allergy to red or processed meat,
vegetarian or vegan,
any religious or personal reason(s) to avoid red and processed meat,
pregnant an/or exclusively breastfeeding, and/or
alcohol or recreational drug abuse

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05274906). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.