N/A
N=23
Red and Processed Meat Effects on the Metabolome and Microbiome
Controlled Feeding Trial · Healthy Eating Index · Red Meat · Meat
Bottom Line
View on ClinicalTrials.gov: NCT05274906 ↗Enrolled (actual)
23
Serious AEs
0.0%
Results posted
Sep 2024
Primary outcome: Primary: Test the Effects of Red and Processed Meat on Aqueous Biomarkers of the Blood Metabolome — 0.87; 0.60; 3.48; 5.66 ratio of day 21 to day 0
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Randomized, cross-over controlled feeding trial testing a Healthy Eating Index 2015 (HEI-2015) diet with and without red and processed meat (Other)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Fred Hutchinson Cancer Center
- Primary completion
- Feb 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Test the Effects of Red and Processed Meat on Aqueous Biomarkers of the Blood Metabolome |
0.87; 0.60; 3.48; 5.66; 0.99; 0.88 | — |
| PRIMARY Test the Effects of Red and Processed Meat on Lipid Biomarkers of the Blood Metabolome |
1.09; 0.98; 1.11; 0.97; 0.89; 0.80 | — |
| PRIMARY Test the Effects of Red and Processed Meat on Biomarkers on the Urine Metabolome |
0.99; 1.09; 1.54; 2.18; 1.16; 1.24 | — |
| PRIMARY Test the Effects of Red and Processed Meat on Gut Microbiome |
0.99; 1.00 | — |
| PRIMARY Test the Effects of Red and Processed Meat on Fecal Bacterial Functional Genes |
0.54; 0.24; 0.07; 0.19; 0.23; 0.11 | — |
Summary
This controlled feeding trial will identify biomarkers in the metabolome and microbiome that may differ when consuming a healthy diet with or without red and processed meat.
Eligibility Criteria
Inclusion Criteria
- Healthy adult,
- 18-50 years of age,
- able to read, speak, and understand English, and
- willing to come to the Fred Hutchinson Cancer Research Center campus twice weekly during study
Exclusion Criteria
- known allergy to red or processed meat,
- vegetarian or vegan,
- any religious or personal reason(s) to avoid red and processed meat,
- pregnant an/or exclusively breastfeeding, and/or
- alcohol or recreational drug abuse
Data sourced from ClinicalTrials.gov (NCT05274906). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.