Phase 4 N=129 Prevention

Toward Zero Prescribed Opioids for Outpatient General Surgery

Opioid Misuse and Addiction · Pain

Bottom Line

View on ClinicalTrials.gov: NCT05327777 ↗

Enrolled (actual)

129

Serious AEs

0.0%

Results posted

Jun 2023

Primary outcome: Primary: Morphine Milligram Equivalents Taken by Participants — 46; 15; 0 morphine milligram equivalents

Study Design & Population

Study type: Interventional
Phase: Phase 4
Interventions: Oxycodone (Drug); Zero Opioid Protocol (Behavioral)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Thomas Jefferson University
Primary completion: Jul 2021

Outcome Measures

Outcome	Result	p-value
PRIMARY Morphine Milligram Equivalents Taken by Participants	46; 15; 0	—
SECONDARY Satisfaction Scores Ranging From 1 - 10	10; 10; 10	—

Summary

Investigators have created an opioid reduction "package" which includes patient education, non-narcotic pain control instructions, and limited (or no) opioid pain prescriptions provided at discharge in an attempt to reduce the number of opioid consumption after outpatient general surgery.

Eligibility Criteria

Inclusion Criteria

Opioid naïve patients
Age > 18
Being scheduled for an outpatient elective inguinal hernia repair or cholecystectomy

Exclusion Criteria

Urgent/emergent status
Previous cholecystostomy tube placement

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05327777). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.