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N/A N=6 Randomized Triple-blind Treatment

Cognitive Behavioral Therapy and Light Therapy

Pulmonary Hypertension · Insomnia · Fatigue

Enrolled (actual)
6
Serious AEs
0.0%
Results posted
Jan 2025
Primary outcome: Primary: Retention Rate — 0; 1; 2 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
CBT-I (Behavioral); Bright Light Therapy (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Pennsylvania
Primary completion
May 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Retention Rate
0; 1; 2

Summary

Cognitive behavioral therapy (CBT-I) is a common treatment for insomnia that does not use medications. While CBT-I is effective for insomnia, it does not tend to improve the waking symptom of fatigue. Another treatment, Bright Light Therapy, is used for treating seasonal depression and sleep disorders, and may improve fatigue and physical activity in individuals with PAH. The purpose of this study to assess the effects of Bright Light Therapy compared to CBT-I to treat insomnia and fatigue in patients with PAH.

Eligibility Criteria

Inclusion Criteria

  • PAH diagnosis
  • Insomnia
  • Fatigue

Exclusion Criteria

  • Untreated obstructive sleep apnea
  • Subjects with left-sided valvular disease
  • Hospitalized or acutely ill
  • Any eye disease such as, but not limited to, cataracts, glaucoma, retinal disorders (e.g. macular degeneration), or previous eye surgery
  • Subjects with photosensitivity (e.g. epilepsy)
  • Manic-depressive psychosis or Bipolar Disorder
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05337943). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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