N/A
Completed N=58
Love Infection: A Dramatized Story Intervention (Telenovela/Soap Opera) for HIV Prevention
Source: ClinicalTrials.gov NCT05358366 ↗Enrolled (actual)
58
Serious AEs
0.0%
Results posted
Sep 2024
Primary outcomePrimary: Mean Condom Use — 0.50; 0.14; 1.30; 0.52 sexual episodes
Summary
Purpose: To test the feasibility, acceptability of the IA intervention (four telenovela episodes), assessment of the mechanisms of action (self-efficacy, narrative engagement, and emotional elicitation) and conduct a randomized controlled pilot study to examine the change in primary outcomes (condom use, HIV testing, Pre-exposure Prophylaxis (PrEP) awareness and use) and secondary outcomes (Substance abuse (SA), intimate partner violence (IPV), and depression comparing 33 intervention- and 33 control Latinas at baseline (T1, pre-intervention), T2 (immediately post-intervention, 1 month) and T3 (3 months after the end of the intervention, with no intervening contact with study staff).
Participants: 66 Latinas ages 18-44 years who report sexual activity with a man in the last 6 months, have internet access from any device, and reside in NC.
Procedures (methods): Participants will be asked to: (1) receive an orientation about the use of the Infección de Amor (IA) telenovela website and access the telenovela website once a week for 4 weeks to watch a telenovela episode and answer some questions about the episode (half hour each week, 2 in total), (2) attend to a one hour-meeting with the research team to complete a baseline survey, (3) complete a survey (on their own) one-month after the baseline survey, and (4) complete another survey (on their own) 4-months after the baseline survey. Participants will complete a structured survey in the first meeting (baseline survey) with a member of the research team and then they will complete the follow-up surveys (1-month and 4-months after baseline) on their own.
Participants can request help to complete these surveys with the help of the research team (online using Zoom or face to face if needed). The moment that participants will access the IA intervention will depend on the group to be assigned by the research team (intervention or control group).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Condom Use |
0.50; 0.14; 1.30; 0.52; 0; 0 | — |
| PRIMARY Number of Participants Who Report Change in PrEP Awareness |
7; 2; 24; 25; 20; 1 | — |
| PRIMARY Number of Participants Who Report Change in PrEP Access |
2; 0; 4; 1; 1; 1 | — |
| PRIMARY Number of Participants Who Report Changes in PrEP Use |
0; 0; 7; 2; 0; 0 | — |
| PRIMARY Number of Participants Who Report Change in HIV Testing |
6; 3; 19; 21; 3; 2 | — |
| PRIMARY Mean Change in HIV Test Perception Score |
34.7; 35.7; 34.6; 36.4; 32.8; 36.1 | — |
| SECONDARY Mean Change in Substance Abuse Score |
2.42; 0.78; 2.32; 0.96; 2.75; 1.23 | — |
| SECONDARY Mean Change in Intimate Partner Violence (IPV) Score |
2.27; 2.78; 2.28; 1.96; 1.79; 1.25 | — |
| SECONDARY Mean Change in Depression (PHQ-9) Score |
5.61; 4.04; 5.65; 2.29; 6.67; 2.36 | — |
| SECONDARY Number of Episodes Watched by Participants |
2; 18; 1; 2; 2; 0 | — |
| SECONDARY Number of Participants Who Are Retained Through All Study Timepoints |
26; 23 | — |
Eligibility Criteria
Inclusion Criteria
- Self-identified as a Latina
- Assigned female gender at birth
- Fluent in English or Spanish
- Between 18 and 44 years old
- Report sexual activity with a man in the last 6 months
- Have internet access from any device
- Reside in NC
Exclusion Criteria
- Unwilling to be part of the study
- Do not read, speak, or understand Spanish or English
- Do not have access to internet
- HIV positive
Data sourced from ClinicalTrials.gov (NCT05358366). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.