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N/A N=191 Randomized Triple-blind Treatment

Healthy And Positive Pathways for Young People With Type 1 Diabetes (HAPPY T1D)

Type 1 Diabetes

Enrolled (actual)
191
Serious AEs
8.1%
Results posted
Mar 2026
Primary outcome: Primary: Time in Range (TIR) — 50.1; 47.2; 53.8; 50.3 Percent of time — p=.224

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Psychoeducation to reduce diabetes distress and improve glycemic outcomes (Behavioral)
Age
Pediatric, Adult · 14+ yrs
Sex
All
Sponsor
Joslin Diabetes Center
Primary completion
Nov 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Time in Range (TIR)
50.1; 47.2; 53.8; 50.3; 56.5; 49.9 .224
SECONDARY
A1c
7.9; 8.1; 7.5; 7.9; 7.6; 7.9 .422
SECONDARY
Diabetes Distress
46.2; 51.6; 42.9; 48.2; 41.3; 46.7 .082
SECONDARY
Attitudes Toward Diabetes Device Use
3.97; 3.92; 3.98; 3.90; 3.93; 4.05 .526

Summary

In this 2-year randomized clinical trial, we will implement and assess the impact of a behavioral/psychoeducational intervention to reduce diabetes distress and improve glycemic outcomes in adolescents and young adults, aged 14-25 years, with T1D in order to optimize their short-term and long-term health.

Eligibility Criteria

Inclusion Criteria

  • Age 14-25 years
  • Diagnosis of type 1 diabetes (according to ADA criteria)
  • Type 1 diabetes duration ≥12 months
  • A1c 7-13%
  • Smartphone or regular access to wifi via computer
  • Fluency in English at a 5th grade level or higher (based on investigator assessment of grade level in school or highest grade level achieved and presence in mainstream academic classes)

Exclusion Criteria

  • Physical or mental health condition that in the determination of the investigators may limit the ability to fully participate in the study (e.g., autism)
  • Participation in another intervention study within the last 3 months
  • Currently pregnant or intending to become pregnant during the study (assessed by self-report)
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05413239). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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