Pancreatic tissue engineering faces vascularization hurdle in type 1 diabetes therapy
New tissue engineering methods aim to improve pancreatic transplants
This narrative review examines pancreatic tissue engineering for type 1 diabetes, highlighting insufficient vascularization as the dominant …
Current pancreas transplants are limited by a shortage of donors and the need for lifelong drugs. New engineering techniques may offer a dif…
CAR technology for autoimmune disorders, infectious diseases, fibrotic lesions, inflammatory bowel disease, and type 1 diabetes is reviewed
Chimeric antigen receptor technology may help treat autoimmune disorders and other conditions
This narrative review discusses the application of chimeric antigen receptor (CAR) technology across autoimmune disorders, infectious diseas…
A narrative review suggests chimeric antigen receptor technology could be useful for treating autoimmune disorders, infectious diseases, and…
scFv-based biologics show potential for immunomodulation in type 1 and type 2 diabetes
Review explores scFv biologics for Type 1 and Type 2 diabetes care
This narrative review explores the potential of single-chain variable fragment (scFv)-based biologics for treating type 1 and type 2 diabete…
This review looks at scFv-based biologics for diabetes. It discusses how these treatments might help with immune control and blood sugar bal…
Meta-analysis finds no link between early-life antibiotics and type 1 diabetes risk
Antibiotics in Pregnancy Don’t Raise Child’s Diabetes Risk, Study Finds
This meta-analysis of early-life antibiotic exposure found no significant association with type 1 diabetes incidence in the general populati…
This large review offers reassurance that standard antibiotic use during pregnancy and infancy is safe regarding type 1 diabetes risk, with …
Early-life antibiotic exposure linked to modest increased risk of childhood type 1 diabetes
Meta-analysis links early-life antibiotic use to higher childhood type 1 diabetes risk
This meta-analysis of early-life antibiotic use found a modest increased risk of childhood type 1 diabetes. Prenatal exposure showed a poole…
A large meta-analysis suggests early antibiotic exposure may slightly raise childhood type 1 diabetes risk, though causality remains unclear…
Women with Type 1 Diabetes have a 2.10 times higher risk of female sexual dysfunction compared to age-matched controls
Women with Type 1 Diabetes face a higher risk of sexual dysfunction than controls
This systematic review and meta-analysis evaluated the prevalence and risk of female sexual dysfunction in women with Type 1 Diabetes. The p…
A large review found that women with Type 1 Diabetes are significantly more likely to experience sexual dysfunction compared to healthy wome…
Systematic review and meta-analysis on probiotics for glycemic control in pediatric type 1 diabetes
New review shows probiotics may help lower blood sugar levels in kids with type 1 diabetes
This systematic review and meta-analysis synthesized evidence on oral probiotics, prebiotics, or synbiotics in children and adolescents with…
A study of 808 children found that taking probiotics helped lower blood sugar and A1C levels. More research is needed to find the best type …
Case report of high-dose ceftazidime in an 84-year-old man with skull base osteomyelitis and type 1 diabetes
High-dose antibiotic shows partial skull base infection resolution
This case report describes an 84-year-old man with type 1 diabetes, vascular comorbidity, and advanced frailty treated for skull base osteom…
An 84-year-old man with diabetes and a rare skull infection saw some improvement with a long antibiotic course, but his condition remained c…
Systematic review finds no difference in hypoglycemia or ketoacidosis between insulin types
Children on insulin may not need newer expensive versions
A meta-analysis of 1,107 children with type 1 diabetes found no significant difference in severe hypoglycemia, ketoacidosis, or serious adve…
A major review finds older human insulin works as safely as newer analogues for children with type 1 diabetes, which could ease costs for fa…
Narrative review discusses CAR-T and HSC therapies for cancer and autoimmune conditions
Cancer Cell Therapy Gets Second Life Against Diabetes and MS
This narrative review examines the scope of chimeric antigen receptor T-cell (CAR-T), CAR-engineered regulatory T cell (CAR-Treg), and hemat…
• CAR-T cells trained to calm overactive immune systems show real promise • People with Type 1 diabetes or multiple sclerosis could benefit …
Semaglutide reduces insulin dose in adults with type 1 diabetes and obesity
Semaglutide Cuts Insulin Needs By Half In Type 1 Diabetes
A post hoc analysis of an RCT found that semaglutide 1 mg/week significantly reduced total daily insulin dose by 22.6% over 26 weeks in adul…
Semaglutide reduces insulin needs quickly in type 1 diabetes patients, offering a new hope for better blood sugar control and weight managem…
Narrative review of transposable element methylation in autoimmune diseases
Genetic elements may link autoimmune diseases to inflammation
This narrative review examines the role of transposable element (TE) methylation and expression in Type 1 diabetes, systemic lupus erythemat…
Changes in certain genetic elements could explain how the body triggers inflammation in diseases like lupus and rheumatoid arthritis.
Research across Diabetes
Related studies from across the Diabetes family.
A 6 dimension and 42 item system provides early risk assessment for high-risk diabetic feet
Experts Develop New Risk Assessment System for Diabetic Feet
This expert consultation and guideline describes the development of an early risk assessment system for high-risk diabetic feet. The consens…
A new assessment system identifies risk factors like nerve damage and circulation to help manage and prevent complications in patients with …
Evaluating the Impact of Digital Health Interventions on Chronic Disease Self-Care Outcomes
Digital health tools show mixed results for managing chronic diseases
Digital tools show promise for heart failure monitoring but lack consistent evidence for improving medication adherence or general diabetes …
New data shows that while digital tools like apps can help heart failure patients monitor their health, they may not improve medication habi…
Pharmacist-led telepharmacy may improve medication adherence and reduce blood pressure in patients with NCDs
Pharmacist Led Telepharmacy May Improve Medication Adherence For Chronic Illness
This systematic review analyzed 21 trials involving 5440 participants to evaluate pharmacist-led telepharmacy for managing non-communicable …
Remote pharmacist services through phone or video may help patients with high blood pressure and diabetes stick to their daily medication pl…
Resveratrol supplementation significantly reduces LDL-C but lacks consistent impact on glycemic indices in type 2 diabetes
Resveratrol fails to improve blood sugar in type 2 diabetes
This umbrella review and meta-analysis of 10 meta-analyses evaluated resveratrol for managing type 2 diabetes. While a significant reduction…
Resveratrol supplements did not lower blood sugar or improve cholesterol in type 2 diabetes, except for a small drop in LDL cholesterol.
Pancreatic cancer involves multilayered mechanisms from environment to immune escape
Review reveals complex causes of pancreatic cancer
This narrative review synthesizes the multilayered mechanisms of pancreatic cancer, including environmental exposure, genetic susceptibility…
Pancreatic cancer arises from a mix of genetics, lifestyle, and inflammation, review finds.
Individualized six-phase antithrombotic strategy leads to left ventricular thrombus resolution and neurological recovery
New strategy helps manage heart blood clots after heart attack
This case report describes an individualized six-phase antithrombotic strategy for a 27-year-old male with myocardial infarction, stroke, hy…
A tailored six-phase treatment plan helped a young man recover fully from a stroke and heart attack while successfully clearing dangerous bl…
High prevalence of microvascular and macrovascular complications among adult Ugandans with diabetes
High rates of diabetes complications found in adult Ugandans
This meta-analysis examined the prevalence of various diabetic complications, including neuropathy and retinopathy, in a large cohort of adu…
More than half of Ugandan adults with diabetes suffer from nerve damage, highlighting a critical need for earlier screening and better care.
SGLT2 inhibitors associated with lower all-cause mortality in heart transplant recipients with type 2 diabetes
SGLT2 inhibitors associated with lower mortality in heart transplant patients
This meta-analysis examined the impact of SGLT2 inhibitor use on outcomes for heart transplant recipients with type 2 diabetes. The authors …
New analysis suggests SGLT2 inhibitors may lower death rates for heart transplant recipients with type 2 diabetes without increasing UTI ris…
Immunometabolic dysregulation drives hyperalgesia and hypoesthesia in diabetic peripheral neuropathy
New research explores how inflammation drives nerve damage in diabetes
This narrative review explores the pathophysiology of diabetic peripheral neuropathy, focusing on how hyperglycemia, lipotoxicity, and intes…
Chronic high blood sugar causes more than just high glucose; it triggers a cycle of inflammation and immune stress that damages nerves.
Single-incision sleeve plus bypass shows short-term safety and metabolic improvement in 3 patients with obesity and T2DM
SILSG-JJB Procedure Shows Promise for Weight Loss and Diabetes
This case report and review describes 3 female patients with severe obesity and type 2 diabetes who underwent single-incision laparoscopic s…
A new surgical approach may help people with severe obesity and Type 2 Diabetes achieve weight loss and better blood sugar levels.
Transcriptomic analysis identifies 337 high-confidence genes associated with Type 2 Diabetes in human pancreatic islets
Meta-analysis reveals 337 genes linked to type 2 diabetes in islets
This meta-analysis of transcriptomic data from human pancreatic islets identified 337 high-confidence T2D-associated genes. The study also d…
A meta-analysis of human pancreatic islets identified 337 high-confidence genes tied to type 2 diabetes, and a 10-gene panel perfectly disti…
Chronic hyperglycemia causes multi-level nerve damage across the peripheral, autonomic, and central nervous systems
Understanding how high blood sugar damages the entire nervous system in diabetes
This narrative review synthesizes how chronic hyperglycemia impacts the entire neuroaxis in patients with diabetes. It details metabolic and…
High blood sugar can damage nerves throughout the whole body. This affects your senses, movement, and internal organs.
Questions about Type 1 Diabetes
Does the FDA approved drug Tzield delay the onset of Stage 3 Type 1 diabetes?
Yes, the FDA-approved drug Tzield (teplizumab) delays the onset of Stage 3 type 1 diabetes in people with Stage 2 disease.
Full answer →Can semaglutide help reduce the total daily insulin dose for adults with Type 1 diabetes?
Yes, semaglutide can reduce total daily insulin dose in adults with type 1 diabetes and overweight or obesity, based on clinical trial and real-world data.
Full answer →All Type 1 Diabetes Articles
- Pancreatic tissue engineering faces vascularization hurdle in type 1 diabetes therapy
- CAR technology for autoimmune disorders, infectious diseases, fibrotic lesions, inflammatory bowel disease, and type 1 diabetes is reviewed
- Meta-analysis finds no link between early-life antibiotics and type 1 diabetes risk
- scFv-based biologics show potential for immunomodulation in type 1 and type 2 diabetes
- Early-life antibiotic exposure linked to modest increased risk of childhood type 1 diabetes
- Women with Type 1 Diabetes have a 2.10 times higher risk of female sexual dysfunction compared to age-matched controls
- Systematic review and meta-analysis on probiotics for glycemic control in pediatric type 1 diabetes
- Case report of high-dose ceftazidime in an 84-year-old man with skull base osteomyelitis and type 1 diabetes
- Systematic review finds no difference in hypoglycemia or ketoacidosis between insulin types
- Narrative review discusses CAR-T and HSC therapies for cancer and autoimmune conditions
- Narrative review of transposable element methylation in autoimmune diseases
- Semaglutide reduces insulin dose in adults with type 1 diabetes and obesity
- Umbrella review identifies risk factors and protective factors for male infertility and semen quality
- Meta-analysis finds slight IQ difference in children with type 1 diabetes versus peers
- Barriers and promoters to CGM and AID use in youth with T1D and public insurance
- FDA Approves Tzield (teplizumab) to Delay Onset of Stage 3 Type 1 Diabetes
- Beta-cell stress responses contribute to early Type 1 diabetes development and disease progression
- Meta-analysis of sex differences in insulin therapy outcomes for adults with Type 1 and Type 2 diabetes
- Systematic review and meta-analysis of integrative therapies for Type 1 Diabetes Mellitus
- Autoimmune Thyroiditis Prevalence Higher in Obese Women With PCOS in Retrospective Cohort Analysis
- Meta-analysis of adjunctive SGLT2 inhibitors in type 1 diabetes shows mixed safety and efficacy signals
- Machine learning model predicts in-hospital hypoglycemia in Chinese adults with type 1 diabetes
- Observational MRI study links impaired hypoglycemia awareness to blunted cerebral blood flow responses in type 1 diabetes
- Cadonilimab therapy in cervical cancer associated with new-onset type 1 diabetes and diabetic ketoacidosis in a case report
- Narrative review examines immune modulation strategies for beta-cell replacement in type 1 diabetes
- Meta-analysis finds high prevalence of adverse outcomes in African women with hyperglycaemia in pregnancy
- Overweight status at diagnosis in Kuwaiti children with new-onset type 1 diabetes is associated with milder clinical presentation and lower HbA1c
- App-supported resistance training linked to lean mass and bone gains in youth with type 1 diabetes
- Individualized insulin strategies may improve glycemic control in pediatric T1DM with exogenous insulin antibody syndrome
- Insulin dose reduction during exercise yields similar glucose effects with ultra-rapid and rapid aspart
- Higher HbA1c linked to reduced cortical thickness, gray matter in youth; effect stronger in deprived neighborhoods
- GLP-1 Receptor Agonist Use in Wolfram Syndrome Shows No Glycemic or BMI Benefit, Common GI Effects
- Lipoprotein(a) shows substantial longitudinal variability in children with type 1 diabetes
- Youth diabetes incidence increased from 2002-2015, with higher rates of increase in minority populations
- Pilot RCT Shows Feasibility of Digital Hypoglycemia Intervention in Type 1 Diabetes
- Tubeless automated insulin delivery reduces HbA1c more than multiple daily injections in type 1 diabetes
- Genetic study links H. pylori susceptibility to HLA and innate immunity genes, suggests causal disease relationships
- Meta-analysis finds 8.33% pooled prevalence of new-onset diabetes after SARS-CoV-2 infection in adults
- Chinese APS-1 patients show recurrent AIRE gene deletion, male predominance, and low classic triad incidence
- GADA test shows high specificity but moderate sensitivity for adult-onset type 1 diabetes