N/A
N=90
Helping HAND: Healing Anorexia Nervosa Digitally
Anorexia Nervosa
Bottom Line
View on ClinicalTrials.gov: NCT05499676 ↗Enrolled (actual)
90
Serious AEs
1.1%
Results posted
May 2026
Primary outcome: Primary: Effectiveness of the Mobile App Conditions, Compared to Referral to Usual Care, in Changing Eating Disorder Psychopathology, as Assessed by the Eating Disorder Examination-Questionnaire. — 3.83; 3.57; 3.52; 3.42 Scores on a scale — p=0.0003
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- SilverCloud Health Mobile Intervention (Device); Social Networking Intervention: Facebook (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- Female
- Sponsor
- Washington University School of Medicine
- Primary completion
- Mar 2025
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Effectiveness of the Mobile App Conditions, Compared to Referral to Usual Care, in Changing Eating Disorder Psychopathology, as Assessed by the Eating Disorder Examination-Questionnaire. |
3.83; 3.57; 3.52; 3.42; 3.20; 3.44 | 0.0003 sig |
| SECONDARY Number of Participants With Any Reported Eating Behaviors in the Mobile App Conditions Compared to Referral to Usual Care. |
23; 22; 23; 18; 15; 19 | 0.950 |
| SECONDARY Effectiveness of the Mobile App Conditions, Compared to Referral to Usual Care, in Changing Body Mass Index (BMI). |
21.0; 22.4; 22.5; 20.7; 21.6; 22.9 | 0.0166 sig |
| SECONDARY Effectiveness of the Mobile App Conditions, Compared to Referral to Usual Care, in Changing Depression, as Assessed by the Patient Health Questionnaire. |
11.3; 12.87; 10.33; 11.31; 10.81; 11.46 | 0.6018 |
| SECONDARY Effectiveness of the Mobile App Conditions, Compared to Referral to Usual Care, in Changing Clinical Impairment, as Assessed by the Clinical Impairment Assessment. |
28.07; 28.97; 27.03; 25.65; 24.88; 27.04 | 0.0005 sig |
Summary
The proposed project will develop and pilot a coached mobile app, including a social networking component, for individuals with anorexia nervosa to use in the post-acute period
Eligibility Criteria
Inclusion Criteria
- Cisgender women who are 18 years old and older, who own a mobile phone, speak English, are U.S. residents, have a BMI greater than or equal to 17, who are connected with a physician (such as a primary care provider), who are not using a feeding tube, and who have been discharged from intensive treatment (i.e., inpatient, residential, partial hospitalization, intensive outpatient) for DSM-5 anorexia nervosa within the past 2 months.
Exclusion Criteria
- Individuals who are not cisgender women.
- Individuals under 18 years old.
- Individuals who do not own a mobile phone.
- Individuals who have not been discharged from intensive treatment (i.e., inpatient, residential, partial hospitalization, intensive outpatient) for DSM-5 anorexia nervosa within the past 2 months).
- Individuals who are not connected with a physician (such as a primary care provider)
- Individuals who have a BMI below 17.0
- Individuals who are currently using a feeding tube
Data sourced from ClinicalTrials.gov (NCT05499676). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.